Form 8.3- ASTRAZENECA PLC

Form 8.3- ASTRAZENECA PLC

BARCLAYS PLC

FORM 8.3

PUBLIC OPENING POSITION DISCLOSURE/DEALING DISCLOSURE BY

A PERSON WITH INTERESTS IN RELEVANT SECURITIES REPRESENTING 1% OR MORE

Rule 8.3 of the Takeover Code (the “Code”)

1. KEY INFORMATION

(a) Identity of the person whose positions/dealings are being disclosed:	Â	Barclays PLC.
(b) Owner or controller of interests and short positions disclosed, if different from 1(a): The naming of nominee or vehicle companies is insufficient	Â	Â
(c) Name of offeror/offeree in relation to whose relevant securities this form relates: Use a separate form for each offeror/offeree	Â	ASTRAZENECA PLC
(d) If an exempt fund manager connected with an offeror/offeree, state this and specify identity of offeror/offeree:	Â	Â
(e) Date position held/dealing undertaken:	Â	30 April 2014
(f) Has the discloser previously disclosed, or are they today disclosing, under the Code in respect of any other party to this offer?	Â	YES: PFIZER INC

2. POSITIONS OF THE PERSON MAKING THE DISCLOSURE

(a) Interests and short positions in the relevant securities of the offeror or offeree to which the disclosure relates following the dealing (if any)

Class of relevant security:	Â	Â	Â	ORD	Â	Â	Â	Â	Â	Â
				Interests		Â		Short Positions		Â
Â		Â		Number		(%)		Number		(%)
(1)		Relevant securities owned
		and/or controlled:		11,234,192		0.89%		5,956,600		0.47%
Â		Â		Â		Â		Â		Â
(2)		Derivatives (other than
		options):		1,317,759		0.10%		4,194,171		0.33%
Â		Â		Â		Â		Â		Â
(3)		Options and agreements to
		purchase/sell:		238,200		0.02%		779,300		0.06%
Â		Â		Â		Â		Â		Â
(4)		TOTAL:
				12,790,151		1.01%		10,930,071		0.86%
Â		Â		Â		Â		Â		Â
Â		Â		Â		Â		Â		Â
Class of relevant security:		Â		ADR		Â		Â		Â
				Interests		Â		Short Positions		Â
Â		Â		Number		(%)		Number		(%)
(1)		Relevant securities owned
		and/or controlled:		219,297		0.02%		105,774		0.01%
Â		Â		Â		Â		Â		Â
(2)		Derivatives (other than
		options):		0		0.00%		0		0.00%
Â		Â		Â		Â		Â		Â
(3)		Options and agreements to
		purchase/sell:		0		0.00%		0		0.00%
Â		Â		Â		Â		Â		Â
(4)		TOTAL:
				219,297		0.02%		105,774		0.01%

If there are positions or rights to subscribe to disclose in more than one class of relevant securities of the offeror or offeree named in 1(c), copy table 2(a) or (b) (as appropriate) for each additional class of relevant security.

3. DEALINGS (IF ANY) BY THE PERSON MAKING THE DISCLOSURE

(a) Purchases and sales

Class of relevant	Â	Purchase/sale	Â	Number of	Â	Price per unit
security		Â		securities		Â
ORD		Purchase		7		46.2330 GBP
ORD		Purchase		27		46.1990 GBP
ORD		Purchase		32		46.2095 GBP
ORD		Purchase		32		46.5300 GBP
ORD		Purchase		32		46.9070 GBP
ORD		Purchase		32		46.9155 GBP
ORD		Purchase		35		46.7405 GBP
ORD		Purchase		36		46.5805 GBP
ORD		Purchase		37		46.6250 GBP
ORD		Purchase		37		46.7280 GBP
ORD		Purchase		40		46.7505 GBP
ORD		Purchase		41		46.8000 GBP
ORD		Purchase		49		46.4050 GBP
ORD		Purchase		50		46.8480 GBP
ORD		Purchase		52		46.2025 GBP
ORD		Purchase		54		46.1800 GBP
ORD		Purchase		54		46.1825 GBP
ORD		Purchase		54		46.1950 GBP
ORD		Purchase		54		46.1995 GBP
ORD		Purchase		54		46.2125 GBP
ORD		Purchase		56		46.8550 GBP
ORD		Purchase		57		46.2175 GBP
ORD		Purchase		57		46.6775 GBP
ORD		Purchase		58		46.5475 GBP
ORD		Purchase		59		46.7525 GBP
ORD		Purchase		63		46.5860 GBP
ORD		Purchase		64		46.0850 GBP
ORD		Purchase		64		46.1760 GBP
ORD		Purchase		64		46.1775 GBP
ORD		Purchase		64		46.1875 GBP
ORD		Purchase		64		46.7325 GBP
ORD		Purchase		64		46.7950 GBP
ORD		Purchase		65		46.2220 GBP
ORD		Purchase		67		46.2225 GBP
ORD		Purchase		67		46.6225 GBP
ORD		Purchase		68		46.2620 GBP
ORD		Purchase		68		46.4600 GBP
ORD		Purchase		71		46.2370 GBP
ORD		Purchase		75		46.4605 GBP
ORD		Purchase		75		46.4625 GBP
ORD		Purchase		75		46.4725 GBP
ORD		Purchase		75		46.5505 GBP
ORD		Purchase		75		46.5975 GBP
ORD		Purchase		76		46.2700 GBP
ORD		Purchase		76		46.8175 GBP
ORD		Purchase		76		46.8225 GBP
ORD		Purchase		76		46.8450 GBP
ORD		Purchase		76		46.8555 GBP
ORD		Purchase		76		46.8625 GBP
ORD		Purchase		76		46.9000 GBP
ORD		Purchase		79		46.7005 GBP
ORD		Purchase		82		46.9500 GBP
ORD		Purchase		83		46.5825 GBP
ORD		Purchase		84		46.7375 GBP
ORD		Purchase		85		46.5920 GBP
ORD		Purchase		85		46.7425 GBP
ORD		Purchase		87		46.7255 GBP
ORD		Purchase		95		46.1905 GBP
ORD		Purchase		95		46.1925 GBP
ORD		Purchase		95		46.6550 GBP
ORD		Purchase		96		46.7775 GBP
ORD		Purchase		99		46.7275 GBP
ORD		Purchase		99		46.7330 GBP
ORD		Purchase		101		46.8500 GBP
ORD		Purchase		101		46.9350 GBP
ORD		Purchase		101		46.9375 GBP
ORD		Purchase		101		46.9425 GBP
ORD		Purchase		102		46.8760 GBP
ORD		Purchase		103		46.7400 GBP
ORD		Purchase		104		46.5730 GBP
ORD		Purchase		104		46.6755 GBP
ORD		Purchase		105		46.2750 GBP
ORD		Purchase		107		46.7850 GBP
ORD		Purchase		108		46.6450 GBP
ORD		Purchase		112		46.7085 GBP
ORD		Purchase		116		46.8825 GBP
ORD		Purchase		120		46.2955 GBP
ORD		Purchase		122		46.1550 GBP
ORD		Purchase		122		46.6985 GBP
ORD		Purchase		126		46.4750 GBP
ORD		Purchase		126		46.4780 GBP
ORD		Purchase		126		46.5080 GBP
ORD		Purchase		126		46.5100 GBP
ORD		Purchase		126		46.5125 GBP
ORD		Purchase		126		46.5150 GBP
ORD		Purchase		126		46.5175 GBP
ORD		Purchase		126		46.5350 GBP
ORD		Purchase		126		46.5775 GBP
ORD		Purchase		126		46.5900 GBP
ORD		Purchase		126		46.5925 GBP
ORD		Purchase		131		46.8805 GBP
ORD		Purchase		132		46.9025 GBP
ORD		Purchase		135		46.5465 GBP
ORD		Purchase		135		46.5875 GBP
ORD		Purchase		141		46.6050 GBP
ORD		Purchase		145		46.2425 GBP
ORD		Purchase		148		46.7170 GBP
ORD		Purchase		148		46.7175 GBP
ORD		Purchase		150		46.5630 GBP
ORD		Purchase		152		46.5525 GBP
ORD		Purchase		152		46.5995 GBP
ORD		Purchase		152		46.8855 GBP
ORD		Purchase		155		46.7130 GBP
ORD		Purchase		155		46.9100 GBP
ORD		Purchase		159		46.2100 GBP
ORD		Purchase		159		46.4650 GBP
ORD		Purchase		159		46.6600 GBP
ORD		Purchase		161		46.6455 GBP
ORD		Purchase		161		46.6575 GBP
ORD		Purchase		161		46.7800 GBP
ORD		Purchase		161		46.8050 GBP
ORD		Purchase		161		46.8125 GBP
ORD		Purchase		161		46.8400 GBP
ORD		Purchase		165		46.5025 GBP
ORD		Purchase		165		46.6425 GBP
ORD		Purchase		173		46.5675 GBP
ORD		Purchase		173		46.9475 GBP
ORD		Purchase		180		46.2275 GBP
ORD		Purchase		180		46.9050 GBP
ORD		Purchase		184		46.5400 GBP
ORD		Purchase		184		46.6580 GBP
ORD		Purchase		186		46.7030 GBP
ORD		Purchase		188		46.2575 GBP
ORD		Purchase		192		46.2050 GBP
ORD		Purchase		201		46.5375 GBP
ORD		Purchase		207		46.6700 GBP
ORD		Purchase		207		46.7269 GBP
ORD		Purchase		212		46.8525 GBP
ORD		Purchase		214		46.7480 GBP
ORD		Purchase		217		46.2375 GBP
ORD		Purchase		225		46.6375 GBP
ORD		Purchase		225		46.7155 GBP
ORD		Purchase		230		46.2550 GBP
ORD		Purchase		231		46.8750 GBP
ORD		Purchase		238		46.5250 GBP
ORD		Purchase		245		46.2950 GBP
ORD		Purchase		249		46.8650 GBP
ORD		Purchase		251		46.5425 GBP
ORD		Purchase		252		46.5200 GBP
ORD		Purchase		252		46.5575 GBP
ORD		Purchase		252		46.6075 GBP
ORD		Purchase		262		46.5950 GBP
ORD		Purchase		262		46.7650 GBP
ORD		Purchase		263		46.7300 GBP
ORD		Purchase		289		46.9214 GBP
ORD		Purchase		295		46.5650 GBP
ORD		Purchase		297		46.6825 GBP
ORD		Purchase		305		46.2250 GBP
ORD		Purchase		307		46.6800 GBP
ORD		Purchase		320		46.7105 GBP
ORD		Purchase		323		46.4800 GBP
ORD		Purchase		340		46.5275 GBP
ORD		Purchase		342		46.6125 GBP
ORD		Purchase		348		46.2900 GBP
ORD		Purchase		365		46.8900 GBP
ORD		Purchase		367		46.8950 GBP
ORD		Purchase		369		46.5700 GBP
ORD		Purchase		369		46.7250 GBP
ORD		Purchase		370		46.2475 GBP
ORD		Purchase		392		46.6905 GBP
ORD		Purchase		393		46.7150 GBP
ORD		Purchase		400		46.5450 GBP
ORD		Purchase		400		46.8850 GBP
ORD		Purchase		402		46.5550 GBP
ORD		Purchase		416		46.6350 GBP
ORD		Purchase		419		46.7350 GBP
ORD		Purchase		436		46.6875 GBP
ORD		Purchase		447		46.8100 GBP
ORD		Purchase		453		46.6955 GBP
ORD		Purchase		455		46.7125 GBP
ORD		Purchase		462		46.5500 GBP
ORD		Purchase		476		46.8350 GBP
ORD		Purchase		480		46.8600 GBP
ORD		Purchase		493		46.5750 GBP
ORD		Purchase		495		46.6925 GBP
ORD		Purchase		515		46.6150 GBP
ORD		Purchase		522		46.2850 GBP
ORD		Purchase		533		46.7450 GBP
ORD		Purchase		538		46.2300 GBP
ORD		Purchase		540		46.8250 GBP
ORD		Purchase		546		46.7055 GBP
ORD		Purchase		581		46.6650 GBP
ORD		Purchase		583		46.6500 GBP
ORD		Purchase		594		46.6750 GBP
ORD		Purchase		600		46.2600 GBP
ORD		Purchase		607		46.6100 GBP
ORD		Purchase		609		46.2350 GBP
ORD		Purchase		639		46.3000 GBP
ORD		Purchase		655		46.6900 GBP
ORD		Purchase		657		509.7123 SEK
ORD		Purchase		701		46.6850 GBP
ORD		Purchase		705		46.6975 GBP
ORD		Purchase		729		46.7025 GBP
ORD		Purchase		800		46.8200 GBP
ORD		Purchase		823		46.5800 GBP
ORD		Purchase		871		46.8800 GBP
ORD		Purchase		875		46.2450 GBP
ORD		Purchase		1,129		510.0916 SEK
ORD		Purchase		1,148		509.5000 SEK
ORD		Purchase		1,162		46.2500 GBP
ORD		Purchase		1,242		510.5000 SEK
ORD		Purchase		1,270		46.7100 GBP
ORD		Purchase		1,477		46.6000 GBP
ORD		Purchase		1,501		46.7050 GBP
ORD		Purchase		1,686		46.7044 GBP
ORD		Purchase		2,000		46.1200 GBP
ORD		Purchase		2,004		46.8700 GBP
ORD		Purchase		2,429		46.6950 GBP
ORD		Purchase		2,734		510.0000 SEK
ORD		Purchase		2,874		46.5994 GBP
ORD		Purchase		3,132		46.7000 GBP
ORD		Purchase		3,234		46.7106 GBP
ORD		Purchase		3,419		46.7500 GBP
ORD		Purchase		3,540		46.7200 GBP
ORD		Purchase		3,979		46.6877 GBP
ORD		Purchase		4,199		46.6579 GBP
ORD		Purchase		4,805		46.7075 GBP
ORD		Purchase		4,818		509.7635 SEK
ORD (traded as ADR)		Purchase		6,850		78.6016 USD
ORD		Purchase		8,629		46.6835 GBP
ORD		Purchase		8,688		508.8790 SEK
ORD		Purchase		8,716		46.6039 GBP
ORD		Purchase		9,885		46.6967 GBP
ORD		Purchase		10,000		46.6420 GBP
ORD		Purchase		10,576		46.6278 GBP
ORD		Purchase		11,943		46.6114 GBP
ORD		Purchase		16,911		46.5448 GBP
ORD		Purchase		20,000		46.5512 GBP
ORD		Purchase		20,545		46.6400 GBP
ORD		Purchase		25,928		46.6118 GBP
ORD		Purchase		26,688		46.6127 GBP
ORD		Purchase		29,148		46.6183 GBP
ORD		Purchase		30,000		46.1631 GBP
ORD		Purchase		37,340		46.5572 GBP
ORD (traded as ADR)		Purchase		49,476		78.6619 USD
ORD		Purchase		63,035		46.6306 GBP
ORD		Purchase		66,223		46.6129 GBP
ORD		Purchase		137,369		46.6668 GBP
ORD		Purchase		150,000		46.2880 GBP
ORD		Purchase		257,360		46.6147 GBP
ORD		Purchase		325,180		46.5725 GBP
ORD		Purchase		331,066		46.5467 GBP
ORD		Purchase		361,789		46.5259 GBP
ORD		Purchase		500,000		46.3284 GBP
ORD		Purchase		500,000		46.7742 GBP
ORD		Purchase		583,582		46.2400 GBP
ORD		Sale		7		46.2330 GBP
ORD		Sale		22		46.7067 GBP
ORD		Sale		27		46.1990 GBP
ORD		Sale		32		46.2095 GBP
ORD		Sale		32		46.5300 GBP
ORD		Sale		32		46.9070 GBP
ORD		Sale		32		46.9155 GBP
ORD		Sale		35		46.7405 GBP
ORD		Sale		36		46.5805 GBP
ORD		Sale		37		46.6250 GBP
ORD		Sale		37		46.7280 GBP
ORD		Sale		40		46.7505 GBP
ORD		Sale		41		46.8000 GBP
ORD		Sale		48		514.0000 SEK
ORD		Sale		49		46.4050 GBP
ORD		Sale		50		46.8480 GBP
ORD		Sale		50		46.9110 GBP
ORD		Sale		52		46.2025 GBP
ORD		Sale		54		46.1800 GBP
ORD		Sale		54		46.1825 GBP
ORD		Sale		54		46.1950 GBP
ORD		Sale		54		46.1995 GBP
ORD		Sale		54		46.2125 GBP
ORD		Sale		56		46.8550 GBP
ORD		Sale		57		46.2175 GBP
ORD		Sale		57		46.6775 GBP
ORD		Sale		58		46.5475 GBP
ORD		Sale		59		46.7525 GBP
ORD		Sale		63		46.5860 GBP
ORD		Sale		64		46.0850 GBP
ORD		Sale		64		46.1760 GBP
ORD		Sale		64		46.1775 GBP
ORD		Sale		64		46.1875 GBP
ORD		Sale		64		46.7325 GBP
ORD		Sale		64		46.7950 GBP
ORD		Sale		65		46.2220 GBP
ORD		Sale		67		46.2225 GBP
ORD		Sale		67		46.6225 GBP
ORD		Sale		68		46.2620 GBP
ORD		Sale		68		46.4600 GBP
ORD		Sale		71		46.2370 GBP
ORD		Sale		75		46.4605 GBP
ORD		Sale		75		46.4625 GBP
ORD		Sale		75		46.4725 GBP
ORD		Sale		75		46.5505 GBP
ORD		Sale		75		46.5975 GBP
ORD		Sale		76		46.2700 GBP
ORD		Sale		76		46.8175 GBP
ORD		Sale		76		46.8225 GBP
ORD		Sale		76		46.8450 GBP
ORD		Sale		76		46.8555 GBP
ORD		Sale		76		46.8625 GBP
ORD		Sale		76		46.9000 GBP
ORD		Sale		79		46.7005 GBP
ORD		Sale		82		46.9500 GBP
ORD		Sale		83		46.5825 GBP
ORD		Sale		84		46.7375 GBP
ORD		Sale		85		46.5920 GBP
ORD		Sale		85		46.7425 GBP
ORD		Sale		87		46.7255 GBP
ORD		Sale		95		46.1905 GBP
ORD		Sale		95		46.1925 GBP
ORD		Sale		95		46.6550 GBP
ORD		Sale		96		46.7775 GBP
ORD		Sale		99		46.7275 GBP
ORD		Sale		99		46.7330 GBP
ORD		Sale		101		46.8500 GBP
ORD		Sale		101		46.9350 GBP
ORD		Sale		101		46.9375 GBP
ORD		Sale		101		46.9425 GBP
ORD		Sale		102		46.8760 GBP
ORD		Sale		103		46.7400 GBP
ORD		Sale		104		46.5730 GBP
ORD		Sale		104		46.6755 GBP
ORD		Sale		105		46.2750 GBP
ORD		Sale		107		46.2550 GBP
ORD		Sale		107		46.7850 GBP
ORD		Sale		108		46.6450 GBP
ORD		Sale		112		46.7085 GBP
ORD		Sale		116		46.8825 GBP
ORD		Sale		120		46.2955 GBP
ORD		Sale		122		46.6985 GBP
ORD		Sale		126		46.4750 GBP
ORD		Sale		126		46.4780 GBP
ORD		Sale		126		46.5080 GBP
ORD		Sale		126		46.5100 GBP
ORD		Sale		126		46.5125 GBP
ORD		Sale		126		46.5150 GBP
ORD		Sale		126		46.5175 GBP
ORD		Sale		126		46.5350 GBP
ORD		Sale		126		46.5775 GBP
ORD		Sale		126		46.5900 GBP
ORD		Sale		126		46.5925 GBP
ORD		Sale		131		46.8805 GBP
ORD		Sale		132		46.9025 GBP
ORD		Sale		135		46.5465 GBP
ORD		Sale		135		46.5875 GBP
ORD		Sale		142		46.2233 GBP
ORD		Sale		145		46.2425 GBP
ORD		Sale		148		46.7170 GBP
ORD		Sale		148		46.7175 GBP
ORD		Sale		150		46.5630 GBP
ORD		Sale		152		46.5525 GBP
ORD		Sale		152		46.8855 GBP
ORD		Sale		155		46.7130 GBP
ORD		Sale		155		46.9100 GBP
ORD		Sale		159		46.2100 GBP
ORD		Sale		159		46.4650 GBP
ORD		Sale		159		46.6600 GBP
ORD		Sale		161		46.6455 GBP
ORD		Sale		161		46.6575 GBP
ORD		Sale		161		46.7800 GBP
ORD		Sale		161		46.8050 GBP
ORD		Sale		161		46.8125 GBP
ORD		Sale		161		46.8400 GBP
ORD		Sale		165		46.5025 GBP
ORD		Sale		165		46.6425 GBP
ORD		Sale		173		46.5675 GBP
ORD		Sale		173		46.9475 GBP
ORD		Sale		180		46.2275 GBP
ORD		Sale		180		46.9050 GBP
ORD		Sale		184		46.5400 GBP
ORD		Sale		184		46.6580 GBP
ORD		Sale		186		46.7030 GBP
ORD		Sale		188		46.2575 GBP
ORD		Sale		192		46.2050 GBP
ORD		Sale		201		46.5375 GBP
ORD		Sale		203		46.6050 GBP
ORD		Sale		207		46.6700 GBP
ORD		Sale		212		46.1550 GBP
ORD		Sale		212		46.8525 GBP
ORD		Sale		214		46.7480 GBP
ORD		Sale		217		46.2375 GBP
ORD		Sale		225		46.6375 GBP
ORD		Sale		225		46.7155 GBP
ORD		Sale		231		46.8750 GBP
ORD		Sale		235		46.2618 GBP
ORD		Sale		238		46.5250 GBP
ORD		Sale		245		46.2950 GBP
ORD		Sale		249		46.8650 GBP
ORD		Sale		251		46.5425 GBP
ORD		Sale		252		46.5200 GBP
ORD		Sale		252		46.6075 GBP
ORD		Sale		262		46.5950 GBP
ORD		Sale		262		46.7650 GBP
ORD		Sale		263		46.7300 GBP
ORD		Sale		295		46.5650 GBP
ORD		Sale		297		46.6825 GBP
ORD		Sale		305		46.2250 GBP
ORD		Sale		307		46.6800 GBP
ORD		Sale		320		46.7105 GBP
ORD		Sale		323		46.4800 GBP
ORD		Sale		340		46.5275 GBP
ORD		Sale		342		46.6125 GBP
ORD		Sale		348		46.2900 GBP
ORD		Sale		365		46.8900 GBP
ORD		Sale		367		46.8950 GBP
ORD		Sale		369		46.5700 GBP
ORD		Sale		369		46.7250 GBP
ORD		Sale		370		46.2475 GBP
ORD		Sale		376		46.2350 GBP
ORD		Sale		392		46.6905 GBP
ORD		Sale		393		46.7150 GBP
ORD		Sale		400		46.5450 GBP
ORD		Sale		400		46.8850 GBP
ORD		Sale		402		46.5550 GBP
ORD		Sale		416		46.6350 GBP
ORD		Sale		419		46.7350 GBP
ORD		Sale		426		46.1200 GBP
ORD		Sale		436		46.6875 GBP
ORD		Sale		447		46.8100 GBP
ORD		Sale		453		46.6955 GBP
ORD		Sale		455		46.7125 GBP
ORD		Sale		462		46.5500 GBP
ORD		Sale		476		46.8350 GBP
ORD		Sale		493		46.5750 GBP
ORD		Sale		495		46.6925 GBP
ORD		Sale		515		46.6150 GBP
ORD		Sale		522		46.2850 GBP
ORD		Sale		533		46.7450 GBP
ORD		Sale		538		46.2300 GBP
ORD		Sale		540		46.8250 GBP
ORD		Sale		546		46.7055 GBP
ORD		Sale		573		46.6545 GBP
ORD		Sale		581		46.6650 GBP
ORD		Sale		583		46.6500 GBP
ORD		Sale		594		46.6750 GBP
ORD		Sale		600		46.2600 GBP
ORD		Sale		607		46.6100 GBP
ORD		Sale		639		46.3000 GBP
ORD		Sale		655		46.6900 GBP
ORD		Sale		701		46.6850 GBP
ORD		Sale		703		46.7103 GBP
ORD		Sale		705		46.6975 GBP
ORD		Sale		729		46.7025 GBP
ORD		Sale		800		46.8200 GBP
ORD		Sale		823		46.5800 GBP
ORD		Sale		871		46.8800 GBP
ORD		Sale		875		46.2450 GBP
ORD		Sale		907		46.6456 GBP
ORD		Sale		976		46.2400 GBP
ORD		Sale		1,162		46.2500 GBP
ORD		Sale		1,270		46.7100 GBP
ORD		Sale		1,280		46.8600 GBP
ORD		Sale		1,356		510.4100 SEK
ORD		Sale		1,477		46.6000 GBP
ORD		Sale		1,727		46.7088 GBP
ORD		Sale		1,801		46.7050 GBP
ORD		Sale		1,854		46.8700 GBP
ORD		Sale		2,429		46.6950 GBP
ORD		Sale		2,825		46.7075 GBP
ORD		Sale		3,069		507.0000 SEK
ORD		Sale		3,132		46.7000 GBP
ORD		Sale		3,419		46.7500 GBP
ORD		Sale		3,540		46.7200 GBP
ORD		Sale		3,761		510.0000 SEK
ORD		Sale		4,252		46.5575 GBP
ORD		Sale		4,773		46.5504 GBP
ORD (traded as ADR)		Sale		6,850		78.6016 USD
ORD		Sale		7,701		509.8319 SEK
ORD		Sale		7,805		46.8539 GBP
ORD		Sale		7,811		46.2413 GBP
ORD		Sale		8,890		46.5591 GBP
ORD		Sale		9,033		46.7102 GBP
ORD		Sale		10,810		46.7074 GBP
ORD		Sale		11,601		46.4127 GBP
ORD		Sale		12,631		46.6400 GBP
ORD		Sale		12,735		46.2464 GBP
ORD		Sale		13,986		46.6715 GBP
ORD		Sale		14,599		46.7031 GBP
ORD		Sale		23,898		46.5410 GBP
ORD (traded as ADR)		Sale		49,476		78.6619 USD
ORD		Sale		51,417		46.5699 GBP
ORD		Sale		53,189		46.7098 GBP
ORD		Sale		95,500		46.5638 GBP
ORD		Sale		147,875		46.6658 GBP
ORD		Sale		150,702		46.6391 GBP
ORD		Sale		173,270		46.5851 GBP
ORD		Sale		346,343		46.5697 GBP
ORD		Sale		354,579		46.5496 GBP
ORD		Sale		425,657		46.5367 GBP

(b) Derivatives transactions (other than options)

Class of	Â	Product	Â	Nature of dealing	Â	Number of	Â	Price per
relevant		description				reference		unit
security		Â		Â		securities		Â
ORD		SWAP		Long		48		512.5658 SEK
ORD		SWAP		Long		372		46.9431 GBP
ORD		SWAP		Long		2,304		46.5037 GBP
ORD		SWAP		Long		3,239		46.8015 GBP
ORD		CFD		Long		3,294		46.2510 GBP
ORD		CFD		Long		5,049		46.6254 GBP
ORD		CFD		Long		9,033		46.7102 GBP
ORD		SWAP		Long		24,634		46.4565 GBP
ORD		SWAP		Long		30,000		46.5941 GBP
ORD		CFD		Long		26,220		46.6905 GBP
ORD		CFD		Long		57,177		46.6089 GBP
ORD		SWAP		Short		152		46.5995 GBP
ORD		SWAP		Short		311		46.6968 GBP
ORD		SWAP		Short		2,302		46.5173 GBP
ORD		CFD		Short		3,071		46.7186 GBP
ORD		CFD		Short		1,685		46.5849 GBP
ORD		CFD		Short		3,380		46.2159 GBP
ORD		SWAP		Short		3,979		46.6877 GBP
ORD		CFD		Short		8,850		46.5734 GBP
ORD		SWAP		Short		30,000		46.1630 GBP
ORD		SWAP		Short		41,392		46.6047 GBP
ORD		SWAP		Short		150,000		46.2880 GBP
ORD		SWAP		Short		500,000		46.3284 GBP
ORD		SWAP		Short		500,000		46.7742 GBP
ORD		SWAP		Short		847,000		46.3094 GBP

(c) Options transactions in respect of existing securities

(i) Writing, selling, purchasing or varying

Product

Â

Writing,

Â

Number

Â

Exercise

Â

Type

Â

Expiry

Â

Option

description

purchasing,

of

price

date

money

selling,

securities

per unit

paid/

varying etc

to which

received

option

per unit

Â

Â

relates

Â

Â

Â

Â

Call Options

Purchasing

900

70 USD

American

19 Jul 2014

9.9000 USD

Call Options

Purchasing

500

80 USD

American

17 May 2014

0.9500 USD

Call Options

Purchasing

100

80 USD

American

21 Jun 2014

2.5500 USD

Call Options

Purchasing

5,200

85 USD

American

19 Jul 2014

1.5011 USD

Call Options

Purchasing

14,000

90 USD

American

19 Jul 2014

0.6000 USD

Call Options

Purchasing

500

90 USD

American

17 Jan 2015

1.5500 USD

Call Options

Purchasing

8,700

95 USD

American

18 Oct 2014

0.5000 USD

Call Options

Selling

300

60 USD

American

17 Jan 2015

19.6000 USD

Call Options

Selling

400

65 USD

American

17 Jan 2015

15.3000 USD

Call Options

Selling

800

72.5 USD

American

21 Jun 2014

7.4000 USD

Call Options

Selling

300

75 USD

American

19 Jul 2014

6.6333 USD

Call Options

Selling

2,000

77.5 USD

American

18 Oct 2014

5.9000 USD

Call Options

Selling

5,100

80 USD

American

19 Jul 2014

3.4270 USD

Call Options

Selling

200

80 USD

American

18 Oct 2014

4.5000 USD

Call Options

Selling

155,000

85 USD

American

19 Jul 2014

1.3800 USD

Put Options

Purchasing

155,000

72.5 USD

American

19 Jul 2014

2.0300 USD

Put Options

Purchasing

600

77.5 USD

American

17 May 2014

1.0166 USD

Put Options

Purchasing

200

80 USD

American

17 May 2014

2.0000 USD

Put Options

Selling

4,700

75 USD

American

21 Jun 2014

2.0468 USD

Put Options

Selling

200

75 USD

American

19 Jul 2014

2.7500 USD

(ii) Exercising

Class of relevant security

Â

Product description e.g. call option

Â

Number of securities

Â

Exercise price per unit

(d) Other dealings (including subscribing for new securities)

Class of relevant security

Â

Nature of dealing e.g. subscription, conversion

Â

Details

Â

Price per unit (if applicable)

The currency of all prices and other monetary amounts should be stated.

Where there have been dealings in more than one class of relevant securities of the offeror or offeree named in 1(c), copy table 3(a), (b), (c) or (d) (as appropriate) for each additional class of relevant security dealt in.

4. OTHER INFORMATION

(a) Indemnity and other dealing arrangements

Details of any indemnity or option arrangement, or any agreement or understanding, formal or informal, relating to relevant securities which may be an inducement to deal or refrain from dealing entered into by the person making the disclosure and any party to the offer or any person acting in concert with a party to the offer: If there are no such agreements, arrangements or understandings, state “none”

NONE

(b) Agreements, arrangements or understandings relating to options or derivatives

Details of any agreement, arrangement or understanding, formal or informal, between the person making the disclosure and any other person relating to: (i) the voting rights of any relevant securities under any option; or (ii) the voting rights or future acquisition or disposal of any relevant securities to which any derivative is referenced: If there are no such agreements, arrangements or understandings, state “none”

NONE

(c) Attachments

Is a Supplemental Form 8 (Open Positions) attached?

Â

YES

Date of disclosure:	Â	1 May 2014
Contact name:		Rajesh Muthanna
Telephone number:		020 3555 4634

Public disclosures under Rule 8 of the Code must be made to a Regulatory Information Service and must also be emailed to the Takeover Panel at [e-mail]. The Panel’s Market Surveillance Unit is available for consultation in relation to the Code’s dealing disclosure requirements on [phone].

The Code can be viewed on the Panel’s website at www.thetakeoverpanel.org.uk.

SUPPLEMENTAL FORM 8 (OPEN POSITIONS)

DETAILS OF OPEN OPTION AND DERIVATIVE POSITIONS, AGREEMENTS TO PURCHASE OR SELL ETC.

Note 5(i) on Rule 8 of the Takeover Code (the “Code”)

1. KEY INFORMATION

Identity of person whose open positions are being disclosed:	Â	Barclays PLC.
Name of offeror/offeree in relation to whose relevant securities the disclosure relates:		ASTRAZENECA PLC

2. OPTIONS AND DERIVATIVES

Product	Â	Writing,	Â	Number	Â	Exercise	Â	Type	Â	Expiry
description		purchasing,		of		price				date
		selling,		securities		per unit
		varying etc		to which
				option
Â		Â		relates		Â		Â		Â
Futures		Selling		-150,000		2.4600		Â		18 Dec 2015
Futures		Selling		-69,000		3418.3728		Â		16 May 2014
Futures		Purchased		21,000		3749.5637		Â		18 Jul 2014
Call Options		Purchased		150,000		4200.0000		American		20 Jun 2014
Call Options		Written		-150,000		4200.0000		American		19 Sep 2014
Call Options		Written		-7,000		4400.0000		American		20 Jun 2014
Call Options		Written		-45,000		4500.0000		American		20 Jun 2014
Put Options		Purchased		-100		25.0000		American		17 Jan 2015
Put Options		Purchased		-400		30.0000		American		17 Jan 2015
Put Options		Purchased		-1,300		30.0000		American		15 Jan 2016
Put Options		Purchased		-700		35.0000		American		17 Jan 2015
Put Options		Purchased		-1,100		37.5000		American		17 Jan 2015
Put Options		Purchased		-1,100		40.0000		American		17 Jan 2015
Put Options		Purchased		-200		42.5000		American		17 Jan 2015
Put Options		Purchased		-6,200		47.5000		American		17 Jan 2015
Put Options		Purchased		-100		50.0000		American		15 Jan 2016
Put Options		Purchased		-400		55.0000		American		15 Jan 2016
Put Options		Purchased		-100		60.0000		American		21 Jun 2014
Put Options		Purchased		-600		60.0000		American		18 Oct 2014
Put Options		Purchased		-700		65.0000		American		21 Jun 2014
Put Options		Purchased		-1,400		65.0000		American		19 Jul 2014
Put Options		Purchased		-13,500		67.5000		American		21 Jun 2014
Put Options		Purchased		-1,600		67.5000		American		19 Jul 2014
Put Options		Purchased		-1,000		70.0000		American		17 Jan 2015
Put Options		Purchased		-155,000		72.5000		American		19 Jul 2014
Put Options		Purchased		-800		75.0000		American		17 May 2014
Put Options		Purchased		-600		77.5000		American		17 May 2014
Put Options		Purchased		-3,000		80.0000		American		16 May 2014
Put Options		Purchased		-9,400		80.0000		American		17 May 2014
Put Options		Purchased		-3,000		80.0000		American		20 Jun 2014
Put Options		Purchased		-1,000		80.0000		American		21 Jun 2014
Put Options		Purchased		-1,895		80.0000		American		18 Jul 2014
Put Options		Written		600		35.0000		American		17 Jan 2015
Put Options		Written		300		35.0000		American		15 Jan 2016
Put Options		Written		1,500		40.0000		American		15 Jan 2016
Put Options		Written		2,000		45.0000		American		17 Jan 2015
Put Options		Written		100		47.5000		American		17 Jan 2015
Put Options		Written		300		50.0000		American		19 Jul 2014
Put Options		Written		300		52.5000		American		17 Jan 2015
Put Options		Written		2,400		55.0000		American		19 Jul 2014
Put Options		Written		200		55.0000		American		18 Oct 2014
Put Options		Written		400		57.5000		American		19 Jul 2014
Put Options		Written		1,500		57.5000		American		17 Jan 2015
Put Options		Written		1,800		60.0000		American		19 Jul 2014
Put Options		Written		6,400		60.0000		American		17 Jan 2015
Put Options		Written		5,000		62.5000		American		21 Jun 2014
Put Options		Written		7,000		62.5000		American		17 Jan 2015
Put Options		Written		2,500		65.0000		American		18 Oct 2014
Put Options		Written		5,300		65.0000		American		17 Jan 2015
Put Options		Written		4,500		67.5000		American		18 Oct 2014
Put Options		Written		2,100		70.0000		American		18 Oct 2014
Put Options		Written		100		72.5000		American		17 May 2014
Put Options		Written		4,700		75.0000		American		21 Jun 2014
Put Options		Written		200		75.0000		American		19 Jul 2014
Put Options		Written		3,900		77.5000		American		19 Jul 2014
Put Options		Written		86,500		80.0000		American		17 May 2014
Put Options		Written		52,700		80.0000		American		21 Jun 2014
Call Options		Purchased		3,000		55.0000		American		17 Jan 2015
Call Options		Purchased		200		60.0000		American		15 Jan 2016
Call Options		Purchased		500		62.5000		American		19 Jul 2014
Call Options		Purchased		300		65.0000		American		17 May 2014
Call Options		Purchased		1,400		65.0000		American		17 Jan 2015
Call Options		Purchased		400		67.5000		American		17 May 2014
Call Options		Purchased		198,200		67.5000		American		21 Jun 2014
Call Options		Purchased		10,000		67.5000		American		19 Jul 2014
Call Options		Purchased		13,800		70.0000		American		21 Jun 2014
Call Options		Purchased		10,400		70.0000		American		19 Jul 2014
Call Options		Purchased		100		70.0000		American		15 Jan 2016
Call Options		Purchased		1,000		75.0000		American		17 May 2014
Call Options		Purchased		2,400		75.0000		American		17 Jan 2015
Call Options		Purchased		500		77.5000		American		17 May 2014
Call Options		Purchased		4,800		80.0000		American		17 May 2014
Call Options		Purchased		3,000		80.0000		American		20 Jun 2014
Call Options		Purchased		5,000		80.0000		American		21 Jun 2014
Call Options		Purchased		1,895		80.0000		American		18 Jul 2014
Call Options		Purchased		6,500		85.0000		American		21 Jun 2014
Call Options		Purchased		5,300		85.0000		American		19 Jul 2014
Call Options		Purchased		2,700		85.0000		American		18 Oct 2014
Call Options		Purchased		12,800		90.0000		American		19 Jul 2014
Call Options		Purchased		500		90.0000		American		17 Jan 2015
Call Options		Purchased		8,700		95.0000		American		18 Oct 2014
Call Options		Written		-300		52.5000		American		15 Jan 2016
Call Options		Written		-200		57.5000		American		17 Jan 2015
Call Options		Written		-800		60.0000		American		19 Jul 2014
Call Options		Written		-3,000		60.0000		American		17 Jan 2015
Call Options		Written		-1,500		62.5000		American		17 Jan 2015
Call Options		Written		-13,500		65.0000		American		19 Jul 2014
Call Options		Written		-400		65.0000		American		15 Jan 2016
Call Options		Written		-500		67.5000		American		19 Jul 2014
Call Options		Written		-100		67.5000		American		18 Oct 2014
Call Options		Written		-500		67.5000		American		17 Jan 2015
Call Options		Written		-1,000		70.0000		American		17 May 2014
Call Options		Written		-2,100		70.0000		American		18 Oct 2014
Call Options		Written		-7,900		70.0000		American		17 Jan 2015
Call Options		Written		-500		72.5000		American		17 May 2014
Call Options		Written		-3,600		72.5000		American		21 Jun 2014
Call Options		Written		-7,400		72.5000		American		19 Jul 2014
Call Options		Written		-2,200		72.5000		American		18 Oct 2014
Call Options		Written		-10,200		75.0000		American		21 Jun 2014
Call Options		Written		-3,000		75.0000		American		18 Jul 2014
Call Options		Written		-3,600		75.0000		American		19 Jul 2014
Call Options		Written		-1,000		75.0000		American		18 Oct 2014
Call Options		Written		-6,500		77.5000		American		19 Jul 2014
Call Options		Written		-2,000		77.5000		American		18 Oct 2014
Call Options		Written		-8,100		80.0000		American		17 May 2014
Call Options		Written		-9,500		80.0000		American		21 Jun 2014
Call Options		Written		-111,100		80.0000		American		19 Jul 2014
Call Options		Written		-400		80.0000		American		18 Oct 2014
Call Options		Written		-5,700		80.0000		American		17 Jan 2015
Call Options		Written		-1,000		80.0000		American		15 Jan 2016
Call Options		Written		-22,400		85.0000		American		21 Jun 2014
Call Options		Written		-155,000		85.0000		American		19 Jul 2014

3. AGREEMENTS TO PURCHASE OR SELL ETC.

Full details should be given so that the nature of the interest or position can be fully understood:

It is not necessary to provide details on a Supplemental Form (Open Positions) with regard to contracts for differences (“CFDs”) or spread bets.

The currency of all prices and other monetary amounts should be stated.

The Panel’s Market Surveillance Unit is available for consultation in relation to the Code’s dealing disclosure requirements on [phone].

The Code can be viewed on the Panel’s website at www.thetakeoverpanel.org.uk.