PDMR Shareholding

NOTIFICATION OF TRANSACTIONS OF DIRECTORS, PERSONS DISCHARGING MANAGERIAL RESPONSIBILITY OR CONNECTED PERSONS This form is intended for use by an issuer to make a RIS notification required by DR 3.1.4R(1). (1) An issuer making a notification in respect of a transaction relating to the shares or debentures of the issuer should complete boxes 1 to 16, 23 and 24. (2) An issuer making a notification in respect of a derivative relating the shares of the issuer should complete boxes 1 to 4, 6, 8,13, 14, 16, 23 and 24. (3) An issuer making a notification in respect of options granted to a director /person discharging managerial responsibilities should complete boxes 1 to 3 and 17 to 24. (4) An issuer making a notification in respect of a financial instrument relating to the shares of the issuer (other than a debenture) should complete boxes 1 to 4, 6, 8, 9, 11, 13, 14, 16, 23 and 24. Please complete all relevant boxes should in block capital letters. 1. Name of the issuer 2. State whether the notification relates to (i) a transaction notified in accordance with DR 3.1.4R(1)(a); or (ii) DR 3.1.4(R)(1)(b) a disclosure made in accordance with section 324 (as extended by section 328) of the Companies Act 1985; or (iii) both (i) and (ii) MICROGEN PLC (i) ONLY 3. Name of person discharging 4. State whether notification relates managerial responsibilities/ to a person connected with a person director discharging managerial responsibilities/director named in 3 and identify the connected person TOM CRAWFORD N/A 5. Indicate whether the notification 6. Description of shares (including is in respect of a holding of the class), debentures or derivatives person referred to in 3 or 4 or financial instruments relating above or in respect of a to shares non-beneficial interest BENEFICIAL INTEREST ORDINARY SHARES OF 5P EACH 7. Name of registered shareholders 8 State the nature of the transaction (s) and, if more than one, the number of shares held by each of them TOM CRAWFORD ACQUISITION OF SHARES AS PART PAYMENT OF SENIOR MANAGEMENT BONUS 9. Number of shares, debentures or 10. Percentage of issued class acquired financial instruments relating to (treasury shares of that class shares acquired should not be taken into account when calculating percentage) 14,925 0.0146% 11. Number of shares, debentures or 12. Percentage of issued class disposed financial instruments relating to (treasury shares of that class shares disposed should not be taken into account when calculating percentage) N/A N/A 13. Price per share or value of 14. Date and place of transaction transaction 0.67P 29 MARCH 2006, UK 15. Total holding following 16. Date issuer informed of transaction notification and total percentage holding following notification (any treasury shares should not be taken into account when calculating percentage) 164,925 - 0.01609% 29 MARCH 2006 If a person discharging managerial responsibilities has been granted options by the issuer complete the following boxes 17 Date of grant 18. Period during which or date on which it can be exercised 19. Total amount paid (if any) for 20. Description of shares or grant of the option debentures involved (class and number) 21. Exercise price (if fixed at time 22. Total number of shares or of grant) or indication that debentures over which options held price is to be fixed at the time following notification of exercise 23. Any additional information 24. Name of contact and telephone number for queries ACQUISITION OF SHARES AS PART G.E. LIDDLE - 01252 772 326 PAYMENT OF SENIOR MANAGEMENT BONUS Name and signature of duly authorised officer of issuer responsible for making notification G.E. LIDDLE __________________________________________________________ Date of notification 29 MARCH 2006 ---------------------------------------------------------- NOTIFICATION OF TRANSACTIONS OF DIRECTORS, PERSONS DISCHARGING MANAGERIAL RESPONSIBILITY OR CONNECTED PERSONS This form is intended for use by an issuer to make a RIS notification required by DR 3.1.4R(1). (1) An issuer making a notification in respect of a transaction relating to the shares or debentures of the issuer should complete boxes 1 to 16, 23 and 24. (2) An issuer making a notification in respect of a derivative relating the shares of the issuer should complete boxes 1 to 4, 6, 8,13, 14, 16, 23 and 24. (3) An issuer making a notification in respect of options granted to a director /person discharging managerial responsibilities should complete boxes 1 to 3 and 17 to 24. (4) An issuer making a notification in respect of a financial instrument relating to the shares of the issuer (other than a debenture) should complete boxes 1 to 4, 6, 8, 9, 11, 13, 14, 16, 23 and 24. Please complete all relevant boxes should in block capital letters. 1. Name of the issuer 2. State whether the notification relates to (i) a transaction notified in accordance with DR 3.1.4R(1)(a); or (ii) DR 3.1.4(R)(1)(b) a disclosure made in accordance with section 324 (as extended by section 328) of the Companies Act 1985; or (iii) both (i) and (ii) MICROGEN PLC (i) ONLY 3. Name of person discharging 4. State whether notification relates managerial responsibilities/ to a person connected with a person director discharging managerial responsibilities/director named in 3 and identify the connected person CLARE GROOM N/A 5. Indicate whether the notification 6. Description of shares (including is in respect of a holding of the class), debentures or derivatives person referred to in 3 or 4 or financial instruments relating above or in respect of a to shares non-beneficial interest BENEFICIAL INTEREST ORDINARY SHARES OF 5P EACH 7. Name of registered shareholders 8 State the nature of the transaction (s) and, if more than one, the number of shares held by each of them CLARE GROOM ACQUISITION OF SHARES AS PART PAYMENT OF SENIOR MANAGEMENT BONUS 9. Number of shares, debentures or 10. Percentage of issued class acquired financial instruments relating to (treasury shares of that class shares acquired should not be taken into account when calculating percentage) 14,925 0.0146% 11. Number of shares, debentures or 12. Percentage of issued class disposed financial instruments relating to (treasury shares of that class shares disposed should not be taken into account when calculating percentage) N/A N/A 13. Price per share or value of 14. Date and place of transaction transaction 0.67P 29 MARCH 2006, UK 15. Total holding following 16. Date issuer informed of transaction notification and total percentage holding following notification (any treasury shares should not be taken into account when calculating percentage) 22,684 - 0.0221% 29 MARCH 2006 If a person discharging managerial responsibilities has been granted options by the issuer complete the following boxes 17 Date of grant 18. Period during which or date on which it can be exercised 19. Total amount paid (if any) for 20. Description of shares or grant of the option debentures involved (class and number) 21. Exercise price (if fixed at time 22. Total number of shares or of grant) or indication that debentures over which options held price is to be fixed at the time following notification of exercise 23. Any additional information 24. Name of contact and telephone number for queries ACQUISITION OF SHARES AS PART G.E. LIDDLE - 01252 772 326 PAYMENT OF SENIOR MANAGEMENT BONUS Name and signature of duly authorised officer of issuer responsible for making notification G.E. LIDDLE __________________________________________________________ Date of notification 29 MARCH 2006

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