Annual Information Update

30 July 2008 THE BIOTECH GROWTH TRUST PLC (the "Company") ANNUAL INFORMATION UPDATE For the 12 months ending Wednesday, 30 July 2008 In accordance with the Prospectus Rule 5.2, the Company reports upon information that it has published or made available to the public over the 12 months ending on 30 July 2008. In accordance with PR5.2.7 some of the announcements during the year may relate to matters which have subsequently changed since the original announcement. Company Announcements With the exception of the daily net asset value announcements, the Company has made the following announcements through PR Newswire (PRN): Date of Publication Summary Description Method of Publication 29 July 2008 Annual Report & Accounts PRN 28 July 2008 AGM Statement PRN 11 July 2008 Transaction in own shares PRN 8 July 2008 Transaction in own shares PRN 1 July 2008 Total voting rights PRN 26 June 2008 Transaction in own shares PRN 24 June 2008 Annual Report & Accounts PRN 20 June 2008 Transaction in own shares PRN 13 June 2008 Final Results PRN 2 June 2008 Total voting rights PRN 2 June 2008 Transaction in own shares PRN 23 May 2008 Transaction in own shares PRN 16 May 2008 Transaction in own shares PRN 9 May 2008 Transaction in own shares PRN 2 May 2008 Transaction in own shares PRN 18 April 2008 Transaction in own shares PRN 11 April 2008 Transaction in own shares PRN 7 April 2008 Holdings in Company PRN 3 April 2008 Transaction in own shares PRN 2 April 2008 Total voting rights PRN 1 April 2008 Compliance with Model Code PRN 28 March 2008 Transaction in own shares PRN 20 March 2008 Transaction in own shares PRN 13 March 2008 Transaction in own shares PRN 7 March 2008 Transaction in own shares PRN 29 February 2008 Transaction in own shares PRN 15 February 2008 Transaction in own shares PRN 14 February 2008 Interim Management Statement PRN 8 February 2008 Transaction in own shares PRN 1 February 2008 Transaction in own shares PRN 25 January 2008 Transaction in own shares PRN 18 January 2008 Transaction in own shares PRN 11 January 2008 Transaction in own shares PRN 9 January 2008 Holdings in Company PRN 4 January 2008 Transaction in own shares PRN 4 January 2008 Portfolio Update PRN 28 December 2007 Transaction in own shares PRN 21 December 2007 Transaction in own shares PRN 14 December 2007 Transaction in own shares PRN 6 December 2007 Transaction in own shares PRN 6 December 2007 Interim Report PRN 16 November 2007 Transaction in own shares PRN 16 November 2007 Interim Results PRN 9 November 2007 Transaction in own shares PRN 8 November 2007 Directorate Change PRN 30 October 2007 Transaction in own shares PRN 26 October 2007 Transaction in Own Shares PRN 11 October 2007 Transaction in Own Shares PRN 3 October 2007 Portfolio Update PRN 2 October 2007 Transaction in Own Shares PRN 1 October 2007 Compliance with Model Code PRN 27 September 2007 Transaction in Own Shares PRN 27 September 2007 Holdings in Company PRN 26 September 2007 Transaction in Own Shares PRN 17 September 2007 Transaction in Own Shares PRN 14 September 2007 Transaction in Own Shares RNS 8 August 2007 Interim Management Statement PRN 8 August 2007 Director declaration PRN Filings at Companies House During the year the following documents were filed at Companies House: Date Document Number Description 28 July 2008 288c Director change of address 7 July 2008 G169 Transaction in own shares 1 July 2008 G169 Transaction in own shares 30 June 2008 G169 Transaction in own shares 26 June 2008 Annual Accounts Annual Report & Accounts 19 June 2008 363s Annual Return 2 June 2008 G169 Transaction in own shares 30 May 2008 G169 Transaction in own shares 7 March 2008 G169 Transaction in own shares 15 February 2008 G169 Transaction in own shares 28 January 2008 G169 Transaction in own shares 7 December 2007 G169 Transaction in own shares 14 November 2007 288b Resignation of a Director 29 October 2007 G169 Transaction in own shares 3 September 2007 G169 Transaction in own shares 23 August 2007 288c Director change of address 16 August 2007 G169 Transaction in own shares Inspection of Documents The Company publishes the following documents on its website at www.biotechgt.com Annual Report Interim Report Interim Management Statement Monthly Fact Sheets Copies of certain documents that are required to be lodged at the FSA in accordance with the Listing Rules, Prospectus Rules and Disclosure Rules are available for inspection at the following address: Financial Services Authority 25 The North Colonnade Canary Wharf London E14 5HS Tel: 020 7676 1000 Copies of documents filed at Companies House are available from: Registrar of Companies Companies House Crown Way Cardiff CF14 3UZ Tel: 0870 3333 636 They may also be downloaded from the website at www.directcompanieshouse.gov.uk Further information may be obtained from: Mark Pope Tel. 020 3008 4913 Frostrow Capital Fax. 020 3043 8889 25 Southampton Buildings London WC2A 1AL Company Secretary

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