Annual Information Update

4 August 2010 THE BIOTECH GROWTH TRUST PLC (the "Company") ANNUAL INFORMATION UPDATE For the 12 months ended 31 July 2010 In accordance with the Prospectus Rule 5.2, the Company reports upon information that it has published or made available to the public over the 12 months ended 31 July 2010. In accordance with PR5.2.7 some of the announcements during the year may relate to matters which have subsequently changed since the original announcement. Company Announcements With the exception of the daily net asset value announcements, the Company has made the following announcements through PR Newswire (PRN): Date of Summary Description Method of Publication Publication 30 July 2010 Annual Financial Report PRN 23 July 2010 Interim Management Statement PRN 16 July 2010 AGM Statement PRN 16 July 2010 Transaction in own shares PRN 1 July 2010 Total Voting Rights PRN 25 June 2010 Holdings in Company PRN 22 June 2010 Holdings in Company PRN 17 June 2010 Annual Financial Report PRN 16 June 2010 Final Results PRN 1 June 2010 Total Voting Rights PRN 4 May 2010 Total Voting Rights PRN 1 April 2010 Total Voting Rights PRN 1 April 2010 Compliance with Model Code PRN 26 March 2010 Transaction in own shares PRN 18 March 2010 Transaction in own shares PRN 1 March 2010 Total Voting Rights PRN 17 February 2010 Interim Management Statement PRN 1 February 2010 Total Voting Rights PRN 12 January 2010 Holdings in Company PRN 4 January 2010 Total Voting Rights PRN 11 December 2009 Holdings in Company PRN 10 December 2009 Holdings in Company PRN 8 December 2009 Holdings in Company PRN 7 December 2009 Holdings in Company PRN 4 December 2009 Result of EGM PRN 4 December 2009 Correction: Result of Equity Issue PRN 1 December 2009 Total Voting Rights PRN 18 November 2009 Doc re Half-yearly Report PRN 16 November 2009 Half-yearly Report PRN 16 November 2009 Proposed Placing and Offer for PRN Subscription 12 November 2009 Preliminary Announcement of Results PRN 2 November 2009 Total Voting Rights PRN 1 October 2009 Compliance with Model Code PRN 1 October 2009 Total Voting Rights PRN 25 September 2009 Transaction in Own Shares PRN 18 September 2009 Transaction in Own Shares PRN 4 September 2009 Transaction in Own Shares PRN 1 September 2009 Total Voting Rights PRN 1 September 2009 Transaction in Own Shares PRN 14 August 2009 Interim Management Statement PRN 5 August 2009 Annual Information Update PRN 3 August 2009 Total Voting Rights PRN Filings at Companies House During the year the following documents were filed at Companies House: Date Document Number Description 12 August 2009 G169 Transaction in own shares 16 October 2009 G169 Transaction in own shares 20 October 2009 G169 Transaction in own shares 20 October 2009 G169 Transaction in own shares 23 March 2010 G169 Transaction in own shares 15 April 2010 SH01 Transaction in own shares 27 April 2010 SH01 Transaction in own shares 17 June 2010 Annual Accounts Annual Report & Accounts 23 July 2010 - Resolutions passed at the AGM 16 June 2010 AR01 Annual Return 31 December 2009 SH01 Return of allotment of shares 8 December 2009 - Resolutions passed at a GM The following documents were filed with the UK Listing Authority Document Viewing Facility on or around the dates indicated. Date Document 17 June 2010 Annual Report & Accounts 18 November 2009 Interim Report & Accounts 23 July 2010 Special Resolutions passed at the AGM on 16 July 2010 8 December 2009 Special Resolutions passed at the GM on 4 December 2009 Inspection of Documents The Company publishes the following documents on its website at www.biotechgt.com Annual Report Interim Report Interim Management Statement Monthly Fact Sheets Copies of the documents that are required to be lodged at the FSA in accordance with the Listing Rules, Prospectus Rules and Disclosure Rules are available for inspection at the following address: Financial Services Authority 25 The North Colonnade Canary Wharf London E14 5HS Tel: 020 7676 1000 Copies of documents filed at Companies House are available from: Registrar of Companies Companies House Crown Way Cardiff CF14 3UZ Tel: 0870 3333 636 They may also be downloaded from the website at www.directcompanieshouse.gov.uk Further information may be obtained from: Mark Pope Frostrow Capital 25 Southampton Buildings London WC2A 1AL Company Secretary Tel. 020 3008 4913 Fax. 020 3043 8889 S:\CLIENTS\BIOG\Stock Exchange Announcements\Annual Information Update\BIOG 12mths to 31 July 2010_announcement.docx

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