Director/PDMR Shareholding

NOTIFICATION OF TRANSACTIONS OF DIRECTORS, PERSONS DISCHARGING MANAGERIAL
RESPONSIBILITY OR CONNECTED PERSONS

This form is intended for use by an issuer to make a RIS notification required
by DR 3.1.4R(1).


(1)    An issuer making a notification in respect of a transaction relating to 
       the shares or debentures of the issuer should complete boxes 1 to 16, 23
       and 24.                                                                 
                                                                               
(2)    An issuer making a notification in respect of a derivative relating to  
       the shares of the issuer should complete boxes 1 to 4, 6, 8, 13, 14, 16,
       23 and 24.                                                              
                                                                               
(3)    An issuer making a notification in respect of options granted to a      
       director/person discharging managerial responsibilities should complete 
       boxes 1 to 3 and 17 to 24.                                              
                                                                               
(4)    An issuer making a notification in respect of a financial instrument    
       relating to the shares of the issuer (other than a debenture) should    
       complete boxes 1 to 4, 6, 8, 9, 11, 13, 14, 16, 23 and 24.              

 

PLEASE COMPLETE ALL RELEVANT BOXES IN BLOCK CAPITAL LETTERS.

1. Name of the issuer:

THE BIOTECH GROWTH TRUST PLC                                                 

2. State whether the notification relates to:

  (i) a transaction notified in accordance with DR 3.1.2R; or
   
 (ii) a disclosure made in accordance with LR9.8.6R(1); or
   
(iii) a disclosure made in accordance with section 793 of the Companies Act 2006

(iii) BOTH (i) AND (ii)                                                        

3. Name of person discharging managerial responsibilities/director:

DR JOHN GORDON (DIRECTOR) AND MRS DIANA MADELEINE GORDON (SPOUSE)              

4. State whether notification relates to a person connected with a person
discharging managerial responsibilities/director named in 3 and identify the
connected person:

AS IN 3 ABOVE                                                                  

5. Indicate whether the notification is in respect of a holding of the person
referred to in 3 or 4 above or in respect of a non-beneficial interest:

AS IN 3 ABOVE                                                                  

6. Description of shares (including class), debentures or derivatives or
financial instruments relating to shares:

ORDINARY 25p SHARES                                                            

7. Name of registered shareholders(s) and, if more than one, the number of
shares held by each of them:

NOT STATED                                                                     

8. State the nature of the transaction:

NOT STATED                                                                     

9. Number of shares, debentures or financial instruments relating to shares
acquired:

DR JOHN GORDON PURCHASED 10,000 ORDINARY SHARES AT 350.25 PENCE PER ORDINARY   
SHARE                                                                          

10. Percentage of issued class acquired (treasury shares of that class should
not be taken into account when calculating percentage):

0.02%                                                                          

11. Number of shares, debentures or financial instruments relating to shares
disposed:

MRS DIANA MADELEINE GORDON SOLD 10,000 ORDINARY SHARES AT 350.00 PENCE PER     
ORDINARY SHARE                                                                 

12. Percentage of issued class disposed (treasury shares of that class should
not be taken into account when calculating percentage):

0.02%                                                                          

13. Price per share or value of transaction:

SEE ABOVE                                                                      

14. Date and place of transaction:

4 MARCH 2013 - LONDON                                                          

15. Total holding following notification and total percentage holding following
notification (any treasury shares should not be taken into account when
calculating percentage):

70,000 ORDINARY SHARES                                                         
                                                                               
0.11%                                                                          

16. Date issuer informed of transaction:

5 MARCH 2013                                                                   

If a person discharging managerial responsibilities has been granted options by
the issuer complete the following boxes

17. Date of grant:

-                                                                              

18. Period during which or date on which it can be exercised:

-                                                                              

19. Total amount paid (if any) for grant of the option:

-                                                                              

20. Description of shares or debentures involved (class and number):

-                                                                              

21. Exercise price (if fixed at time of grant) or indication that price is to
be fixed at the time of exercise:

-                                                                              

22. Total number of shares or debentures over which options held following
notification:

-                                                                              

23. Any additional information:



24. Name of contact and telephone number for queries:

MARK POPE, FOR AND ON BEHALF OF FROSTROW CAPITAL LLP, COMPANY SECRETARY        
                                                                               
TEL: [phone]                                                            

Name and signature of duly authorised officer of issuer responsible for making
notification:

         MARK POPE                                                             

Date of notification:

5 MARCH 2013                                                                   

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