Holding(s) in Company

For filings with the FCA include the annex                                               
                                                                                         
For filings with issuer exclude the annex                                                
                                                                                         
                                                                                         
                                                                                         
TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARESi                                          
                                                                                         
                                                                                         
                                                                                         
1. Identity of the issuer or the underlying issuer              The Biotech Growth Trust 
of existing shares to which voting rights are                              Plc           
attached:ii                                                                              
                                                                                         
2 Reason for the notification (please tick the appropriate box or boxes):                
                                                                                         
An acquisition or disposal of voting rights                                         X    
                                                                                         
An acquisition or disposal of qualifying financial instruments which may result          
in the acquisition of shares already issued to which voting rights are attached          
                                                                                         
An acquisition or disposal of instruments with similar economic effect to                
qualifying financial instruments                                                         
                                                                                         
An event changing the breakdown of voting rights                                         
                                                                                         
Other (please specify):                                                                  
                                                                                         
3. Full name of person(s) subject to the                   Newton Investment Management  
notification obligation:iii                                            Ltd.              
                                                                                         
4. Full name of shareholder(s)                                                           
 (if different from 3.):iv                                N/A                            
                                                                                         
5. Date of the transaction and date on                                                   
which the threshold is crossed or                                  25 July 2014          
reached: v                                                                               
                                                                                         
6. Date on which issuer notified:                                  28 July 2014          
                                                                                         
7. Threshold(s) that is/are crossed or                           Falling below 5%        
reached: vi, vii                                                                         
                                                                                         


 

8. Notified details: GB0000385517                                                                       
                                                                                                        
A: Voting rights attached to shares viii, ix                                                            
                                                                                                        
Class/type   Situation previous              Resulting situation after the triggering transaction       
of           to the triggering                                                                          
shares       transaction                                                                                
                                                                                                        
                                                                                                        
if possible  Number             Number       Number       Number of voting         % of  voting rights x
using        of                 of           of shares    rights                                        
the ISIN     Shares             Voting                                                                  
CODE                            Rights                                                                  
                                             Direct       Direct xi  Indirect xii  Direct Indirect      
                                                                                                        
                                                                                                        
Closed-End                                                                                              
Fund                                                                                                    
             3,580,174          3,580,174    3,080,174    3,080,174  N/A           4.57%    N/A         
GB0000385517                                                                                            
                                                                                                        
                                                                                                        
                                                                                                        
                                                                                                        
                                                                                                        
B: Qualifying Financial Instruments                                                                     
                                                                                                        
Resulting situation after the triggering transaction                                                    
                                                                                                        
Type of financial Expiration     Exercise/                Number of voting               % of voting    
instrument        date xiii      Conversion Period xiv    rights that may be             rights         
                                                          acquired if the                               
                                                          instrument is                                 
                                                          exercised/ converted.                         
                                                                                                        
N/A                                                                                                     
                                                                                                        
                                                                                                        
                                                                                                        
C: Financial Instruments with similar economic effect to Qualifying Financial                           
Instruments xv, xvi                                                                                     
                                                                                                        
Resulting situation after the triggering transaction                                                    
                                                                                                        
Type of       Exercise price Expiration Exercise/      Number of voting       % of voting rights xix, xx  
financial                    date     Conversion     rights instrument                                  
instrument                   xvii     period xviii   refers to                                          
                                                                                                        
                                                                                                        
                                                                                                        
                                                                            Nominal          Delta      
N/A                                                                                                     
                                                                                                        
                                                                                                        
                                                                                                        
                                                                                                        
Total (A+B+C)                                                                                           
                                                                                                        
Number of voting rights                          Percentage of voting rights                            
                                                                                                        
3,080,174                                        4.57%                                                  
                                                                                                        


 

9. Chain of controlled undertakings through which the voting rights and/or the          
financial instruments are effectively held, if applicable: xxi                          
                                                                                        
                                                                                        
                                                                                        
Newton Investment Management Ltd. holds these shares as a discretionary fund            
manager.                                                                                
                                                                                        
                                                                                        
                                                                                        
Proxy Voting:                                                                           
                                                                                        
10. Name of the proxy holder:                                                    N/A    
                                                                                        
11. Number of voting rights proxy holder will cease                              N/A    
to hold:                                                                                
                                                                                        
12. Date on which proxy holder will cease to hold                                N/A    
voting rights:                                                                          
                                                                                        
                                                                                        
                                                                                        
                                                                                        
13. Additional information:                                                             
                                                                           N/A          
                                                                                        
14. Contact name:                                                       Ivan Arias      
                                                                                        
                                                                      516-338-3370      
15. Contact telephone number: