Issue of Equity

THE BIOTECH GROWTH TRUST PLC                          

                                  22 May 2013                                  

                         Allotment of Ordinary Shares                          

THE BIOTECH GROWTH TRUST PLC (the "Company") announces the allotment of 200,000
Ordinary shares of 25p each fully paid from its block listing authority.

These shares were issued today at a price of 407.25 pence per share, which
equates to a premium to the estimated net asset value at the time of
transaction of 0.7%. The net asset value per Ordinary share at the close of
business on 21 May 2013 was 402.12 pence per share.

Following this issue, the Company has the ability to issue a further 930,000
Ordinary shares under its block listing facility.

Following this transaction the Company hereby notifies the market that it has
in issue 67,606,347 Ordinary shares of 25p each all with voting rights. No
shares were held in treasury at the date of announcement.

The figure of 67,606,347 may be used by shareholders as the denominator for the
calculation by which they may determine if they are required to notify their
interest in, or change to their interest in, the Company under the FSA's
Disclosure and Transparency Rules.

Enquiries:

Mark Pope

Frostrow Capital LLP

Tel: [phone]