Issue of Equity

THE BIOTECH GROWTH TRUST PLC 14 March 2013 Allotment of Ordinary Shares - Clarification THE BIOTECH GROWTH TRUST PLC (the "Company") confirms that further to the announcement made on 12 March 2013 regarding the allotment of 200,000 Ordinary shares of 25p each fully paid, such shares will now be allotted under the Company's block listing authority and not under a separately applied for listing as indicated in the original announcement. Following this issue, the Company has the ability to issue a further 4,480,000 Ordinary shares under its block listing facility. Following this transaction the Company hereby notifies the market that it has in issue 64,056,347 Ordinary shares of 25p each all with voting rights. No shares were held in treasury at the date of announcement. The figure of 64,056,347 may be used by shareholders as the denominator for the calculation by which they may determine if they are required to notify their interest in, or change to their interest in, the Company under the FSA's Disclosure and Transparency Rules. Enquiries: Mark Pope Frostrow Capital LLP Tel: 020 3 008 4913
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