Issue of Equity

THE BIOTECH GROWTH TRUST PLC                          

                                21 January 2014                                

                         Allotment of Ordinary Shares                          

THE BIOTECH GROWTH TRUST PLC (the "Company") announces the allotment of 100,000
Ordinary shares of 25p each fully paid from its block listing authority.

These shares were issued today at a price of 530.50 pence per share, which
equates to a premium to the estimated net asset value at the time of
transaction of 0.7%. The net asset value per Ordinary share at the close of
business on 20 January 2014 was 527.02 pence per share.

Following this issue, the Company has the ability to issue a further 6,058,134
Ordinary shares its block listing facility.

Following this transaction the Company hereby notifies the market that it has
in issue 68,886,347 Ordinary shares of 25p each all with voting rights. No
shares were held in treasury at the date of announcement.

The figure of 68,886,347 may be used by shareholders as the denominator for the
calculation by which they may determine if they are required to notify their
interest in, or change to their interest in, the Company under the FCA's
Disclosure and Transparency Rules.

Enquiries:

Victoria Streater
Frostrow Capital LLP
Tel: [phone]