Net Asset Value(s)

THE BIOTECH GROWTH TRUST PLC

NET ASSET VALUE

The estimated un-audited net asset value per share, calculated in accordance with the guidelines of the Association of Investment Companies, for The Biotech Growth Trust PLC at the close of business on 3 November 2016 was 661.57p (ex income) 662.47p (cum income).

For and on behalf of the Board

Frostrow Capital LLP

Secretary

4 November 2016