Net Asset Value(s)

THE BIOTECH GROWTH TRUST PLC

NET ASSET VALUE

The estimated un-audited net asset value per share, calculated in accordance with the guidelines of the Association of Investment Companies, for The Biotech Growth Trust PLC at the close of business on 6 December 2016 was 727.72p (ex income) 729.04p (cum income).

For and on behalf of the Board

Frostrow Capital LLP

Secretary

7 December 2016