Result of Equity Issue

NOT FOR RELEASE, PUBLICATION OR DISTRIBUTION, IN WHOLE OR IN PART, DIRECTLY OR INDIRECTLY, IN OR INTO OR FROM THE UNITED STATES, AUSTRALIA, CANADA, THE REPUBLIC OF SOUTH AFRICA OR JAPAN. The Biotech Growth Trust PLC 4 December 2009 Results of Placing and Offer for Subscription The Board of The Biotech Growth Trust PLC (the `Company') announces the results of the Company's recent Placing and Offer for Subscription. The Company will issue 16,009,579 New Ordinary Shares raising approximately £ 23.9 million of additional funds for the Company. As set out in the Prospectus, the Issue Price has been calculated as at the close of business on 2 December 2009 at 149.18p per New Ordinary Share. All valid applications under the Offer for Subscription will be satisfied in full. The net proceeds of the Issue will be invested in accordance with the Company's investment policy. Following the Issue of the New Ordinary Shares the Company will have 66,137,042 Ordinary Shares in issue. Application has been made to the UK Listing Authority for all the New Ordinary Shares to be admitted to the Official List. Application has also been made for such New Ordinary Shares to be admitted to trading on the London Stock Exchange. It is expected that such admissions will become effective and that dealings in the New Ordinary Shares will commence on 9 December 2009. Capitalised terms which are not defined in this announcement are defined in the Prospectus published on 16 November 2009. Enquiries Grant Challis 020 3008 4912 Frostrow Capital LLP Jane Lewis 020 3100 0295 Winterflood Investment Trusts The distribution of this announcement and/or the Prospectus in certain jurisdictions may be restricted by law. No action has been taken by the Company or Winterflood Securities that would permit an offer of the New Ordinary Shares or possession or distribution of this announcement and/or the Prospectus or any other offering or publicity material in any jurisdiction where action for that purpose is required, other than in the United Kingdom. Persons into whose possession this announcement and/or the Prospectus comes should inform themselves about and observe any such restrictions. Any failure to comply with these restrictions may constitute a violation of the securities laws of any such jurisdiction. Neither this announcement nor the Prospectus and any accompanying documents constitute an offer to sell, or the solicitation of an offer to subscribe for or buy, shares in any jurisdiction in which such offer or solicitation is unlawful and none of them are for distribution in or into the United States, Australia, Canada, the Republic of South Africa or Japan. The New Ordinary Shares described in the Prospectus have not been, and will not be, registered under the United States Securities Act of 1933 (as amended) (the "Securities Act") or the securities laws of any state of the United States or under any of the applicable securities laws of Australia, Canada, the Republic of South Africa or Japan. Accordingly, subject to certain exceptions, the New Ordinary Shares may not be offered, sold or delivered, directly or indirectly, in or into the United States, Australia, Canada, the Republic of South Africa or Japan or to or for the account or benefit of any US person (within the meaning of Regulation S under the Securities Act), or any person resident in Australia, Canada, the Republic of South Africa or Japan. In addition, the Company has not been and will not be registered under the United States Investment Company Act of 1940, as amended and investors will not be entitled to the benefits of such Act.
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