Transaction in Own Shares

For immediate release 15 October 2010 THE BIOTECH GROWTH TRUST PLC (the "Company") MARKET PURCHASE OF COMPANY'S OWN SHARES Notification is given, pursuant to the authority granted at the Annual General Meeting of the Company held on 16 July 2010 to make market purchases of the Company's own shares up to an aggregate maximum of 9,887,383 that a market total of 113,929 Ordinary shares of 25p each in the capital of the Company were purchased today for cancellation by the Company at a price of 155.00 p per share. Following this transaction and in conformity with the provisions of the Transparency Directive, the Company hereby notifies the market that; the total number of Ordinary shares that the Company has in issue, less the total number of Ordinary shares bought back for cancellation by the Company following such purchase, and therefore, the total number of voting rights in the Company is 65,755,880. The Company does not currently hold any Ordinary shares in treasury. The figure of 65,755,880 may be used by shareholders as the denominator for the calculation by which they may determine if they are required to notify their interest in, or change to their interest in, the Company under the FSA's Disclosure and Transparency Rules. For and on behalf of Frostrow Capital LLP Company Secretary For further information, please contact: Tracy Arthur Frostrow Capital LLP Tel: 020 3 008 4914
UK 100

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