New Letting Agreement

Immediate Release: Wednesday 12 November 2008

              CLS Holdings PLC ("CLS") Announces a New Letting at              

                    Maximilian Forum, Martinsried, Germany                     

CLS is pleased to announce a further letting of 1,200 sq m (12,917 sq ft) at
Maximilian Forum to MediGene AG, a biotech company who concentrates on
researching, developing, and commercialising novel drugs in two therapeutic
areas: cancer and autoimmune diseases.

The lease (1,200 sq m) is for a term of eight years with an option to prolong
for five years at the end of the fixed term. There is no break option. The
annual rent is €152,000 (£123,356) with annual indexation to German CPI.

MediGene AG now occupy (including this letting) a total area of 5,970 sq m
(64,583 sq ft) at Maximilian Forum which generates a total rent of €892,320 per
annum (£724,162 per annum).

Sten Mortstedt, Executive Chairman of CLS, commented:

"We are delighted that Medigene have the requirement for further space within
this property and we look forward to our continued relationship with them."

                                    -ends-                                     

For further information, please contact:

Sten Mortstedt, Executive Chairman

Henry Klotz, Chief Executive Officer

CLS Holdings plc

Tel: [phone]

www.clsholdings.com