Holding(s) in Company

The Company has been notified today that the Co-operative Insurance Society
Limited holds as beneficial owner, or has an interest in, 2,295,000 ordinary
shares of Oxford Instruments plc as at the close of business on 23 August 2006,
this being equal to 4.72% of the relevant issued share capital. The decrease in
our percentage holding was as a result of the following transaction:

Date                      Transaction Type           Number of Ordinary Shares 
                                                                               
23/8/2006                 Sale                       450,000                   

Co-operative Insurance Society Limited is a limited partner in Aberforth
Limited Partnership 1A and is interested in 2,295,000 shares as a result of
this participation.