Holding(s) in Company

Oxford Instruments plc has been notified that:-

Schroders plc now holds Indirect voting rights of 6,003,889 which represents
12.16% of the issued share capital of the Company.

The Registered Holders of these voting rights are as follows:


  Schroder Investment Management Limited    5,456,799

  Schroder Investment Management North
  America Limited                             545,090

  Schroder & Co Limited                         2,000


11 March 2008

Jo Young

Company Secretarial Assistant

Oxford Instruments plc

TEL: [phone]