Holding(s) in Company

For filings with the FSA include the annex                                     
                                                                               
For filings with issuer exclude the annex                                      

TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARESi                                

1. Identity of the issuer or the underlying       Oxford Instruments plc       
issuer of existing shares to which voting                                      
rights are attached: ii                                                        

2 Reason for the notification (please tick the appropriate box or boxes):      

An acquisition or disposal of voting rights                               x    
                                                                               
An acquisition or disposal of qualifying financial instruments which           
may result in the acquisition of shares already issued to which voting         
rights are attached                                                            
                                                                               
An acquisition or disposal of instruments with similar economic effect         
to qualifying financial instruments                                            
                                                                               
An event changing the breakdown of voting rights                               
                                                                               
Other (please                                                                  
specify):                                                                      

3. Full name of person(s) subject to               BlackRock, Inc.             
the notification obligation: iii                                               
                                                                               
4. Full name of shareholder(s) (if                                             
different from 3.):iv                                                          
                                                                               
5. Date of the transaction and date                24th July 2012              
on which the threshold is crossed or                                           
reached: v                                                                     
                                                                               
6. Date on which issuer notified:                  26th July 2012              
                                                                               
7. Threshold(s) that is/are crossed          Holding has gone below 15%        
or reached: vi, vii                                                            

8. Notified details:
A: Voting rights attached to shares viii, ix

Class/type of  Situation previous           Resulting situation after          
shares          to the triggering                 the triggering               
                   transaction                     transaction                 
                                                                               
if possible               Number                 Number          % of voting   
using           Number      of      Number         of             rights x     
the ISIN CODE     of      Voting      of         voting                        
                Shares    Rights    shares       rights                        
                                                                               
                                    Direct  Direct  Indirect   Direct  Indirect
                                              xi       xii                     
                                                                               
GB0006650450   7,252,451 7,252,451 N/A      N/A     6,943,823 N/A      12.36%  

B: Qualifying Financial Instruments                                            
                                                                               
Resulting situation after the triggering transaction                           

Type of financial Expiration     Exercise/      Number of voting   % of voting 
   instrument     date xiii  Conversion Period rights that may be    rights    
                                    xiv         acquired if the                
                                                 instrument is                 
                                                   exercised/                  
                                                   converted.                  
                                                                               

C: Financial Instruments with similar economic effect to Qualifying Financial  
Instruments xv, xvi                                                            
                                                                               
Resulting situation after the triggering transaction                           

Type of finan  Exercise Expiration Exercise/  Number of voting    % of voting   
     cial       price   date xvii  Conversion rights instrument  rights xix, xx 
  instrument                         period       refers to                     
                                     xviii                                      
                                                                                
                                                                Nominal   Delta 
                                                                                
     CFD                                          1,406,289     2.50%    2.50%  

Total (A+B+C)                                                                  
                                                                               
        Number of voting rights               Percentage of voting rights      
                                                                               
               8,350,112                                14.86%                 

9. Chain of controlled undertakings through which the voting rights and/or the 
financial instruments are effectively held, if applicable: xxi                 
                                                                               
BlackRock Investment Management (UK) Limited - 8,350,112 (14.86%)              

Proxy Voting:                                                                  
                                                                               
10. Name of the proxy holder:                                                  
                                                                               
11. Number of voting rights proxy                                              
holder will cease to hold:                                                     
                                                                               
12. Date on which proxy holder will                                            
cease to hold voting rights:                                                   

13. Additional information:                     Oxford Instruments plc         
                                                                               
14. Contact name:                                 Susan Johnson-Brett          
                                                                               
                                                  (Company Secretary)          
                                                                               
15. Contact telephone number:                        01865 393 200