Holding(s) in Company

For filings with the FSA include the annex                                     
                                                                               
For filings with issuer exclude the annex                                      

TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARESi                                

1. Identity of the issuer or the underlying       Oxford Instruments plc       
issuer of existing shares to which voting                                      
rights are attached: ii                                                        

2. Reason for the notification (please tick the appropriate box or boxes):      

An acquisition or disposal of voting rights                               x    
                                                                               
An acquisition or disposal of qualifying financial instruments which           
may result in the acquisition of shares already issued to which voting         
rights are attached                                                            
                                                                               
An acquisition or disposal of instruments with similar economic effect         
to qualifying financial instruments                                            
                                                                               
An event changing the breakdown of voting rights                               
                                                                               
Other (please                                                                  
specify):                                                                      

3. Full name of person(s) subject to  Henderson Global Investors               
the notification obligation: iii                                               
                                                                               
4. Full name of shareholder(s) (if                                             
different from 3.):iv                                                          
                                                                               
5. Date of the transaction and date   07 November 2014                         
on which the threshold is crossed or                                           
reached: v                                                                     
                                                                               
6. Date on which issuer notified:     10 November 2014                         
                                                                               
7. Threshold(s) that is/are crossed   5% (please refer to section 13)          
or reached: vi, vii                                                            


8. Notified details:

A: Voting rights attached to shares viii, ix

Class/type of  Situation previous  Resulting situation after                   
shares         to the triggering   the triggering                              
               transaction         transaction                                 
                                                                               
if possible              Number             Number            % of voting      
using          Number    of        Number   of                rights x         
the ISIN CODE  of        Voting    of       voting                             
               Shares    Rights    shares   rights                             
                                                                               
ORD GBP0.05                        Direct   Direct  Indirect  Direct   Indirect
                                            xi      xii                        
                                                                               
GB0006650450   2,979,557 2,979,557                  2,861,804          4.99%   


B: Qualifying Financial Instruments                                            
                                                                               
Resulting situation after the triggering transaction                           

Type of financial Expiration Exercise/         Number of voting   % of voting  
instrument        date xiii  Conversion Period rights that may be rights       
                             xiv               acquired if the                 
                                               instrument is                   
                                               exercised/                      
                                               converted.                      
                                                                               


C: Financial Instruments with similar economic effect to Qualifying Financial  
Instruments xv, xvi                                                            
                                                                               
Resulting situation after the triggering transaction                           

Type of        Exercise Expiration Exercise/  Number of voting  % of voting     
financial      price    date xvii  Conversion rights instrument rights xix, xx  
instrument                         period     refers to                         
                                   xviii                                        
                                                                                
                                                                Nominal  Delta  
                                                                                
CFD                                           126,415           0.22%           



Total (A+B+C)                                                                  
                                                                               
Number of voting rights                 Percentage of voting rights            
                                                                               
2,988,219                               5.21%                                  



9. Chain of controlled undertakings through which the voting rights and/or the 
financial instruments are effectively held, if applicable: xxi                 
                                                                               


Proxy Voting:                                                                  
                                                                               
10. Name of the proxy holder:                                                  
                                                                               
11. Number of voting rights proxy                                              
holder will cease to hold:                                                     
                                                                               
12. Date on which proxy holder will                                            
cease to hold voting rights:                                                   

13. Additional information:             This disclosure is due to a decrease in
                                        ordinary share holding below the 5%    
                                        threshold. The combined holding still  
                                        remains within the 5% threshold level. 
                                                                               
14. Contact name:                                 Susan Johnson-Brett          
                                                                               
15. Contact telephone number:                        01865 393 200