Holding(s) in Company

For filings with the FSA include the annex                                     
                                                                               
For filings with issuer exclude the annex                                      

TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARESi                                

1. Identity of the issuer or the underlying       Oxford Instruments plc       
issuer of existing shares to which voting                                      
rights are attached: ii                                                        

2 Reason for the notification (please tick the appropriate box or boxes):      

An acquisition or disposal of voting rights                               x    
                                                                               
An acquisition or disposal of qualifying financial instruments which           
may result in the acquisition of shares already issued to which voting         
rights are attached                                                            
                                                                               
An acquisition or disposal of instruments with similar economic effect         
to qualifying financial instruments                                            
                                                                               
An event changing the breakdown of voting rights                               
                                                                               
Other (please                                                                  
specify):                                                                      

3. Full name of person(s) subject to  Henderson Global Investors               
the notification obligation: iii                                               
                                                                               
4. Full name of shareholder(s) (if                                             
different from 3.):iv                                                          
                                                                               
5. Date of the transaction and date   26 September 2014                        
on which the threshold is crossed or                                           
reached: v                                                                     
                                                                               
6. Date on which issuer notified:     29 September 2014                        
                                                                               
7. Threshold(s) that is/are crossed   Holding has gone above 5%                
or reached: vi, vii                                                            

8. Notified details:
A: Voting rights attached to shares viii, ix

Class/type of  Situation         Resulting situation after                     
shares         previous          the triggering                                
               to the triggering transaction                                   
               transaction                                                     
if possible                                                                    
using                   Number             Number             % of voting      
the ISIN CODE  Number   of       Number    of                 rights x         
               of       Voting   of        voting                              
               Shares   Rights   shares    rights                              
                                                                               
                                 Direct    Direct   Indirect  Direct   Indirect
                                           xi       xii                        
                                                                               
GB0006650450   Below 5% Below 5%                    2,979,557          5.20%   

B: Qualifying Financial Instruments                                            
                                                                               
Resulting situation after the triggering transaction                           

Type of financial Expiration Exercise/         Number of voting   % of voting  
instrument        date xiii  Conversion Period rights that may be rights       
                             xiv               acquired if the                 
                                               instrument is                   
                                               exercised/                      
                                               converted.                      
                                                                               

C: Financial Instruments with similar economic effect to Qualifying Financial  
Instruments xv, xvi                                                            
                                                                               
Resulting situation after the triggering transaction                           

Type of        Exercise Expiration Exercise/  Number of voting  % of voting     
financial      price    date xvii  Conversion rights instrument rights xix, xx  
instrument                         period     refers to                         
                                   xviii                                        
                                                                                
                                                                Nominal  Delta  
                                                                                
CFD                                           146,869           0.25%           

Total (A+B+C)                                                                  
                                                                               
Number of voting rights                 Percentage of voting rights            
                                                                               
3,126,426                               5.45%                                  

9. Chain of controlled undertakings through which the voting rights and/or the 
financial instruments are effectively held, if applicable: xxi                 
                                                                               

Proxy Voting:                                                                  
                                                                               
10. Name of the proxy holder:                                                  
                                                                               
11. Number of voting rights proxy                                              
holder will cease to hold:                                                     
                                                                               
12. Date on which proxy holder will                                            
cease to hold voting rights:                                                   

13. Additional information:                     Oxford Instruments plc         
                                                                               
14. Contact name:                                 Susan Johnson-Brett          
                                                                               
15. Contact telephone number:                        01865 393 200