Holding(s) in Company

TR-1: Notifications of Major Interests in Shares

1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached:

Oxford Instruments PLC

2. Reason for notification (yes/no)

An acquisition or disposal of voting rights

Yes

An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached

No

An acquisition or disposal of instruments with similar economic effect to qualifying financial instruments

No

An event changing the breakdown of voting rights

No

Other (please specify): Voluntary baseline disclosure in line with the UK implementation of the Amended Transparency Directive

No

3. Full name of person(s) subject to notification obligation:

Ameriprise Financial, Inc. and its group

4. Full name of shareholder(s) (if different from 3):

HSBC Global Custody Nominee (UK) Limited Nortrust Nominees LTD Securities Services Nominees Limited State Street Bank & Trust Boston State Street Nominees Limited Vidacos Nominees Ltd

5. Date of transaction and date on which the threshold is crossed or reached:

26 January 2017

6. Date on which issuer notified:

27 January 2017

7. Threshold(s) that is/are crossed or reached:

Above the threshold of 11%

8: Notified Details

A: Voting rights attached to shares

Class/type of shares If possible use ISIN code

Situation previous to the triggering transaction

Resulting situation after the triggering transaction

Number of shares

Number of voting rights

Number of shares

Number of voting rights

Percentage of voting rights

Direct

Direct

Indirect

Direct

Indirect

GB0006650450

5,785,267

5,785,267

31,506

31,506

6,477,061

0.055%

11.303%

B: Qualifying Financial Instruments

Resulting situation after the triggering transaction

Type of financial instrument

Expiration date

Exercise/ conversion period

No. of voting rights that may be acquired if the instrument is exercised/converted.

Percentage of voting rights

C: Financial Instruments with similar economic effect to Qualifying Financial Instruments

Resulting situation after the triggering transaction

Type of financial instrument

Exercise Price

Expiration date

Exercise / conversion period

No. of voting rights instrument refers to

Percentage of voting rights

Nominal

Delta

Total (A+B+C)

Number of voting rights

Percentage of voting rights

6,508,567

11.358%

9. Chain of controlled undertakings through which the voting rights and /or the financial instruments are effectively held, if applicable:

Threadneedle Asset Management Limited (11.358%) Threadneedle Asset Management Limited is wholly owned by TC Financing Limited, which is itself wholly owned by Threadneedle Asset Management Holdings Limited, which is itself wholly owned by TAM UK Holdings Limited, which is itself wholly owned by Threadneedle Holdings Limited,  which is itself wholly owned by Threadneedle Asset Management Holdings SARL, which is itself wholly owned by Ameriprise International Holdings GmbH, which is itself wholly owned by Ameriprise Financial, Inc.

Proxy Voting:

10. Name of proxy holder:

N/A

11. Number of voting rights proxy holder will cease to hold:

N/A

12. Date on which proxy holder will cease to hold voting rights:

N/A

13. Additional information:

The Shares referred to in section 9 of this form are held in portfolios and funds managed on a discretionary basis by the entities set out in section 9. Please note that the Shares are held through certain nominee companies.

14 Contact name:

Susan Johnson-Brett Company Secretary

15. Contact telephone name:

01865 393 200