Holding(s) in Company

5 August 2005

The Company has been notified today for the purposes of Section 198 of the
Companies Act 1985 that Devon County Council has a material interest in 6.080%
of the issued share capital of Oxford Instruments plc, this interest arises as
a result of their relationship with Hermes Focus Asset Management Limited.

The shares to which this notification relates are registered as follows:

Registered Holder                                  Percentage of Holding       
                                                                               
Chase Nominees Limited                             6.080%