Total Voting Rights

Oxford Instruments plc - Voting Rights and Capital Update

In conformity with the Disclosure and Transparency Rules we would like to
notify the market of the following:

Oxford Instruments plc advises that since 4 October 2010 its capital has
increased by 4,264 ordinary shares with voting rights.

Therefore, the total number of voting rights in Oxford Instruments plc as at 1
November 2010 is 49,843,907.

The above figure (49,843,907) may be used by shareholders as the denominator
for the calculations by which they will determine if they are required to
notify their interest in, or a change to their interest in, Oxford Instruments
plc under the FSA's Disclosure and Transparency Rules.

Susan Johnson-Brett

Company Secretary

Oxford Instruments plc

1 November 2010

Direct dial: 01865 393324

Email: [e-mail]