Board Changes, Placing and Change of Broker

Physiomics plc ("Physiomics" or "the Company") 1 September 2006 Board changes Placing Appointment of broker Board Changes Physiomics announces the resignation with immediate effect of its chairman, David Evans. John Pool, a director of the Company, will assume the role of Chairman for the time being. The Company also announces the resignation from the board of David Collins (Finance Director) and David Fell (non-executive Director). Professor Fell, a recognised expert in systems biology, will remain closely linked to the Company as he continues to direct the technical programme. The board would like to express its gratitude to David Evans, David Collins and David Fell for their significant contribution to the Company. Physiomics is pleased to announce the appointment of Edward Oliver as Finance Director and Duncan Lipscombe as a non-executive Director with immediate effect. Edward is a Chartered Accountant with considerable experience both in professional practice and in industry. Formerly a senior partner at the London based firm of Chartered Accountants, AGN Shipleys, Edward Oliver has since 2002 provided consultancy and advisory services to companies through his firm, Olivers. Edward Oliver is a director of AIM companies Sareum Holdings plc, Angel Biotechnology Holdings plc and Zyzygy plc. Duncan Lipscombe joins the board as a non-executive Director following a successful career as an entrepreneur and director of a family business. Since disposing of a significant interest in his family fast food chain established over a 30 year period, he has served as a director of AIM quoted Zyzygy plc. Placing These board changes were conditional on further funding being made available to the Company. The Company is currently undertaking a placing of up to 142,947,040 Physiomics ordinary shares at price of 0.3p per share to raise cash of £226,000 and in lieu of fees and debt of £202,841. The funds raised will be used to continue developing the Company's existing business and to enable it to progress a number of acquisition opportunities. A number of directors and former directors have agreed to subscribe for shares as part of the placing in lieu of fees, including Dr Paul Harper who will be subscribing for 7,525,357 shares (at a value of £22,576.07) and David Evans who will be subscribing for 5,327,667 shares (at a value of £15,983.00). By virtue of their value, these placings constitute related party transactions. The independent directors consider, having consulted with the Company's nominated adviser, that the terms of the transaction are fair and reasonable insofar as the Company's shareholders are concerned. The placing is conditional on shareholder consent, and a notice convening an extraordinary general meeting to give the directors the authority to issue these shares will be sent to shareholders shortly. Change of broker The Company is pleased to announce that it has appointed Seymour Pierce Ellis Limited as its broker with immediate effect. Information on new directors Edward Morgan Oliver, aged 64, is or has been, a director or partner of the following organisations within the past five years: Present Past Angel Biotechnology Holdings plc ILP Realty (UK) Ltd Sareum Holdings plc SAL 2003 Ltd Zyzygy plc Shake-a-Leg Limited Angel Biotechnology Limited AGN Shipleys (a partnership) Marinetrack Limited Nice Tech Limited Sareum Limited Olivers (a sole trader) Duncan John Lipscombe, aged 58, is or has been, a director of the following companies within the past five years: Present Past Zyzygy plc Fish'n Chick'n Limited Marinetrack Limited Fish'n Chick'n Holdings Limited Nice Tech Limited There is no other information that falls to be disclosed under Schedule 2 paragraph (g) of the AIM Rules. For further information: Paul Harper 07747 842446

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Physiomics (PYC)
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