Preliminary Announcement

NEWS RELEASE 28 November 2008 FINSBURY WORLDWIDE PHARMACEUTICAL TRUST PLC Unaudited Preliminary Results for the six months ended 30 September 2008 Finsbury Worldwide Pharmaceutical Trust PLC today announces its interim results for the six months ended 30 September 2008. Financial Highlights 30 September 31 March % Change 2008 2008 Shareholders' funds £254.7m £224.8m +13.3 Net asset value per share - basic 584.1p 486.6p +20.0 Net asset value per share - 560.3p 482.4p +16.1 diluted (for warrants) Share price 515.0p 457.0p +12.7 Warrant price 44.5p 27.5p +61.8 Discount of share price to diluted 8.1% 5.3% - net asset value per share Benchmark Index * 7,643.7 7,049.7 +8.4 Gearing # 12.4% 1.8% - Total Expense Ratio (annualised) 1.2% 1.3% - * Datastream World Pharmaceutical and Biotechnology Index, total return, sterling adjusted. #Calculated using the Association of Investment Companies' definition (prior charges as a percentage of net assets). Attached: * Chairman's Statement * Review of Investments * Income Statement * Reconciliation of Movements in Shareholders' Funds * Balance Sheet * Cash Flow Statement * Notes to the Financial Statements For further information please contact: Martin Smith, Finsbury Worldwide Pharmaceutical Trust PLC 020 3 008 4913 Mark Pope, Frostrow Capital LLP 020 3008 4913Chairman's Statement Performance In my first Chairman's Statement, I am delighted to report that despite the severe effects of the economic slowdown on global financial markets the Company has performed well, both in relative and absolute terms during the period under review. The six month period has been an extremely challenging one for stock markets as a whole and, against a background of turbulent market conditions particularly towards the end of the summer, the Datastream World Pharmaceutical & Biotechnology Index measured in sterling terms on a total return basis, rose by 8.4% as the healthcare sector was able to provide some insulation from the significant declines seen in other equity sectors. Against this background of difficult market conditions, I am pleased to report that the Company's undiluted net asset value per share rose by 20.0% over the same period, an outperformance of some 11.6%. This outperformance was derived principally from the Company's holdings in biotechnology stocks which performed strongly when compared to larger capitalisation pharmaceutical stocks, the latter having been held back due to a combination of weak drug development pipelines, low R&D productivity and the prospect of an increase in patent expirations commencing in 2010. The Company's performance was also helped by a strengthening U.S. dollar; during the half year it appreciated 10.3% against sterling. The Company's share price rose over the period by 12.7% as the discount of share price to net asset value per share widened slightly from 5.3% at 31 March 2008 to 8.1% at the interim stage. The difficult market environment has continued post the half year end and the Company's net asset value per share and share price fell by c. 5.0% in October compared to a small rise in the benchmark index. Early November, however, has seen a recovery in the Company's performance. It is pleasing to note that for the calendar year to 31 October 2008, the Company's share price performance (total return) was ranked fifth out of 247 UK listed investment companies (source: Winterflood Securities Limited). Share Capital The Company continues to exercise its power to buy-back shares in order to support the discount control mechanism and enhance net asset value per share. During the six months under review the Company repurchased a total of 2,595,750 shares at a cost of £12.6m (including expenses) to be held in treasury. On 23 July 2008, all of the shares held in treasury, totalling 2,679,750 shares, were cancelled; the Board confirms that any shares held in treasury will be cancelled following the Annual General Meeting each year. As at 30 September 2008, the Company held 812,000 shares in treasury. The annual exercise date for the Company's warrants occurred on 31 July 2008, at which time a total of 13,070 warrants were exercised, raising £61,000. The remaining 10.7m warrants have a final exercise date of 31 July 2009 at an exercise price 464.0p per share which compares to the current share price of 482.00p per share. Revenue and Dividends The revenue return for the period was £614,000 (Six months ended 30 September 2007: 674,000) and no interim dividend is declared (Six months ended 30 September 2007: nil). VAT The position with regard to the repayment of VAT remains as described in the Chairman's Statement in the Annual Report & Accounts for the year ended 31 March 2008. We continue to work towards a settlement with the Company's previous Manager, Close Investments Limited and will report on developments as they arise. Outlook Market turbulence has resulted in unprecedented write-downs in financial assets and losses for many of the world's largest banks leading to a shortage of liquidity within the financial sector. When this is combined with the prospect of a deflationary environment and with many governments and individuals still financially over-stretched, a further slowdown in economic growth may be expected. Against this background, merger and acquisition activity within the pharmaceutical and biotechnology sectors is expected to continue and will be a key strategic focus for the Company. On balance, it is not expected that Barack Obama's victory in the U.S. Presidential Election will be a significant factor for the industry in the future. Your Board remains cautious in its outlook but it continues to believe that the underlying secular trends are positive for the healthcare sector overall and that current market conditions will offer interesting buying opportunities. Martin Smith Chairman 25 November 2008 Review of Investments (Companies held in the investment portfolio are shown in bold type) Performance Amidst a collapsing broader equity market triggered by the worst global financial crisis in decades, we are pleased to report that the Company posted a strong increase of 20.0% in its undiluted net asset value per share during the period, well ahead of the benchmark increase of 8.4%. Our strategy of emphasising investments in the biotechnology sector to a greater extent than traditional "big pharma" companies paid dividends during this period as the biotechnology sector increased while pharmaceutical stocks declined slightly on average. Our top individual contributors to performance reflect the success of several different investment strategies: ImClone Systems is an example of our focus on mergers and acquisition ("M&A") candidates, Vertex Pharmaceuticals' performance reflects investor enthusiasm for their exciting novel treatment for Hepatitis C, and both Schering-Plough and Amgen reflect contrarian "value play" investments in stocks which were indiscriminately sold by the market because of overblown concerns about key marketed products. Contribution by Investment - Excluding Options Contribution Contribution per Share (p) * for the six months £'000 Top Five contributors ImClone Systems 7,344 16.40 Schering-Plough 3,720 8.31 Tepnel Life Sciences 3,220 7.19 Vertex Pharmaceuticals 3,059 6.83 Amgen 3,027 6.76 45.49 Bottom Five contributors Roche Holdings (1,454) (3.25) Amylin (1,177) (2.63) BioMarin Pharmaceutical (1,135) (2.53) Par Pharmaceutical (1,075) (2.40) Biogen Idec (650) (1.45) (12.26) based on the weighted average number of the Company's shares in issue during the six months ended 30 September 2008 (44,783,068) Source: Frostrow Capital LLP Sector Developments The market's performance during the period proved somewhat parabolic, with depressed conditions at the beginning and end of the period interposed by a strong rally in July. The spring months proved treacherous, particularly for smaller capitalisation companies as investor risk appetite diminished amidst the credit crisis. Financial market conditions were difficult for biotechnology companies, and the pace of total financing raised by the biotech sector declined nearly 65.0% from the previous year. During July however, the healthcare sector rallied strongly thanks to a combination of resurgent M&A activity and strong fund flows driven by increasingly favourable investor sentiment towards the sector. This rotation into healthcare generally, and biotechnology in particular, is reminiscent of the 1990/1991 economic slowdown, a period with many parallels to today's declining housing market, financial market stresses, rising corporate and individual default rates and poor economic growth. The biotechnology sector posted extraordinary gains during this period, with the Amex Biotechnology Index increasing 46% in 1990 and over 190% in 1991 (both in US$ terms). Markets declined towards the end of the summer months as the credit crisis accelerated and the financial markets generally started to unravel. However the healthcare sector has been able to offer a modest degree of insulation from the precipitous declines seen in other equity sectors thanks to several fundamental underpinnings of the industry: products which are generally non-discretionary consumer purchases, historically low valuations, continuing robust levels of M& A activity providing support for biotech companies in particular, and an unexpectedly quiet election cycle with fewer attacks on "big pharma " companies than we have come to expect during U.S. Presidential election years. In fact we believe that Barack Obama's victory in the U.S. Presidential race will not be a crucial determinant of industry fortunes in the coming years, as he favours increased healthcare coverage (favourable to industry) and increased government influence on drug prices (unfavourable to industry). We hope that the new Democrat administration will bring a welcome changing of the guard at the U.S. Food and Drug Administration ("FDA"), where the situation has gone from bad to worse as drugs under evaluation are increasingly getting delayed or rejected. The bar for outright drug approval is at historical highs, and 2008 is on track to have among the lowest level of new drug approvals in history. An example of the current FDA morass is the blood-thinning agent Prasugrel, being developed in the U.S. by Eli Lilly. The FDA had an original deadline for rendering a decision last June, and notified the company that it would require a 90 day extension to late September. The revised deadline has come and gone with no word from the FDA about a decision. Investors typically assume the worst in these situations and punish the stock prices of companies caught up in these delays. Strategy Review Our M&A theme yielded strong results during the period and continues to be a key strategic focus for the Company. The recent surge in acquisitions coupled with high premiums for the acquired companies demonstrate continued strong demand from "big pharma" companies as they look to smaller biotechs to offset their generally low R&D productivity and pipeline gaps. As shown in the table below, the past six months have seen over a dozen acquisitions of smaller drug companies, with acquisition premiums ranging from 15% to 233%. In addition to these smaller deals, there have been several blockbuster announcements such as Teva's US$9 billion bid (including debt) for Barr Pharmaceuticals, Roche's US$44 billion bid for 100% ownership of Genentech, and a bidding war for ImClone between Bristol-Myers Squibb and Eli Lilly. Both ImClone and Genentech were significant holdings when the deals were announced. Eventually Lilly triumphed with a US$6.5 billion bid, and we expect the offer price for Genentech, currently US$89, will also be raised before the acquisition process is concluded by Roche. Recent Biotechnology Acquisition Announcements Announce Date Target Acquirer Deal Size Premium Paid 06/10/08 ImClone Eli Lilly US$6.5 billion 51% 25/07/08 Acambis Sanofi Aventis US£275 million 65% 23/07/08 Arius Research RocheHoldings $119 million 15% (CAD) 15/07/08 Lev ViroPharma US$443 million 49% Pharmaceuticals 10/07/08 Speedel Novartis US$880 million 94% 08/07/08 SGX Eli Lilly US$64 million 119% Pharmaceuticals 07/07/08 APP Fresenius US$3.6 billion 29% Pharmaceuticals 03/07/08 Jerini Shire US$521 million 73% 23/06/08 Barrier Stiefel US$148 million 136% Therapeutics Laboratories 09/06/08 Third Wave Hologic US$580 million 7% Technologies 05/06/08 Tercica Ipsen US$665 million 104% 29/05/08 Kosan Bristol-MyersSquibb US$190 million 233% 12/05/08 Iomai Intercell US$189 million 128% 22/04/08 Sirtris GlaxoSmithKline US$720 million 84% 11/04/08 Millennium Takeda US$8.8 billion 53% Another key investment theme for the Company is our expectation for significant price/earnings multiple expansion at the larger biotechnology companies as investors properly discount the future earnings growth potential of these companies. The second quarter was a strong period for these "big biotechs", as companies such as Genentech, Genzyme and Biogen Idec announced strong EPS growth and reiterated future EPS growth expectations of 20-25% per year. Finally, during the past few months we have taken advantage of the difficult market conditions to add exposure to a selection of "fallen angels": development stage companies with promising compounds that had fallen 50% or more from their highs. The number of holdings has remained relatively concentrated at approximately 35, exclusive of unquoted investments and options contracts. The approximate geographic distribution of the assets is 80% North America, 15% Europe and 5% Far East including Japan. Consistent with the Company's mandate, we are currently invested 60% in larger companies and 40% in smaller capitalisation companies. Our large capitalisation holdings are weighted slightly in favour of the biotechnology sector versus traditional "big pharma" companies, while our smaller capitalisation holdings emphasise biotechnology companies but also include a selection of generic pharmaceuticals, diagnostics companies and specialty pharmaceutical investments. Samuel D. Isaly OrbiMed Capital LLC Investment Manager Income Statement For the six months ended 30 September 2008 (Unaudited) (Unaudited) (Audited) Six months ended Six months ended Year ended 30 September 2008 30 September 2007 31 March 2008 Revenue Capital Total Revenue Capital Total Revenue Capital Total £'000 £'000 £'000 £'000 £'000 £'000 £'000 £'000 £'000 Gains/(losses) - 47,367 47,367 - 15,373 15,373 - (16,666) (16,666) on investments held at fair value through profit or loss Exchange - (3,090) (3,090) - 1,024 1,024 - 1,332 1,332 (losses)/gains on currency balances Income from 1,208 - 1,208 1,363 - 1,363 3,404 - 3,404 investments held at fair value through profit or loss (note 2) Investment (55) (1,052) (1,107) (65) (1,244) (1,309) (122) (2,323) (2,445) management and management fee (note 3) Operating (289) - (289) (304) - (304) (708) - (708) expenses Net return/ 864 43,225 44,089 994 15,153 16,147 2,574 (17,657) (15,083) (loss) before finance charges and taxation Finance (8) (150) (158) (35) (658) (693) (51) (976) (1,027) charges Net return/ 856 43,075 43,931 959 14,495 15,454 2,523 (18,633) (16,110) (loss) on ordinary activities before taxation Taxation on (242) 88 (154) (285) 140 (145) (782) 372 (410) net return/ (loss) on ordinary activities Net return/ 614 43,163 43,777 674 14,635 15,309 1,741 (18,261) (16,520) (loss) on ordinary activities after taxation Return/(loss) 1.4p 96.4p 97.8p 1.3p 28.9p 30.2p 3.5p (37.1)p (33.6)p per share - basic (note 4) Return/(loss) 1.4p 95.2p 96.6p 1.3p 28.5p 29.8p 3.5p (37.1p) (33.6)p per share - diluted (note 4) The total column of this statement is the Income Statement of the Company. The revenue and capital return columns are supplementary to this and are prepared under guidance published by the Association of Investment Companies. All revenue and capital items in the above statement derive from continuing operations. The Company has no recognised gains and losses other than those shown above and therefore no separate statement of total recognised gains and losses have been presented. No operations were acquired or discontinued during the period. Reconciliation of Movements in Shareholders' Funds For the six months ended 30 September 2008 (Unaudited) Called-up Share Warrant Capital Capital Revenue Total £ share premium reserve reserve redemption reserve '000 Six months ended capital £ account £'000 £'000 reserve £ £'000 '000 £'000 '000 30 September 2008 At 31 March 2008 11,772 117,639 7,426 81,611 3,008 3,327 224,783 Net return from - - - 43,163 - 614 43,777 ordinary activities Dividends paid in - - - - - (1,344) (1,344) respect of year ended 31 March 2008 Proceeds from 3 58 - - - - 61 exercise of warrants Transfer from - 9 (9) - - - - warrant reserve following exercise of warrants Shares purchased (670) - - (12,582) 670 - (12,582) including expenses At 30 September 11,105 117,706 7,417 112,192 3,678 2,597 254,695 2008 (Unaudited) Called-up Share Warrant Capital Capital Revenue Total £ share premium reserve reserve redemption reserve '000 Six months ended capital £ £'000 £'000 reserve £ £'000 '000 account '000 30 September 2007 £'000 At 31 March 2007 14,401 117,565 7,436 130,724 375 3,130 273,631 Net return from - - - 14,635 - 674 15,309 ordinary activities Dividends paid in - - - - - (1,544) (1,544) respect of year ended 31 March 2007 Proceeds from 4 64 - - - - 68 exercise of warrants Transfer from - 10 (10) - - - - warrant reserve following exercise of warrants Shares purchased (946) - - (19,077) 946 - (19,077) including expenses At 30 September 13,459 117,639 7,426 126,282 1,321 2,260 268,387 2007 (Audited) Called-up Share Warrant Capital Capital Revenue Total £ share premium reserve reserve redemption reserve '000 Year ended capital £ £'000 £'000 reserve £ £'000 '000 account '000 31 March 2008 £'000 At 31 March 2007 14,401 117,565 7,436 130,724 375 3,130 273,631 Net/(loss)return - - - (18,261) - 1,741 (16,520) from ordinary activities Dividends paid in - - - - - (1,544) (1,544) respect of year ended 31 March 2007 Proceeds from 4 64 - - - - 68 exercise of warrants Transfer from - 10 (10) - - - - warrant reserve following exercise of warrants Shares purchased (2,633) - - (30,852) 2,633 - (30,852) including expenses At 31 March 2008 11,772 117,639 7,426 81,611 3,008 3,327 224,783 Balance Sheet As at 30 September 2008 (Unaudited) (Unaudited) (Audited) 30 September 30 September 31 March 2008 2007 2008 £'000 £'000 £'000 Fixed assets Investments held at fair value through 284,207 283,534 220,587 profit or loss 11,133 6,312 10,244 M & A Basket - OTC Swap 295,340 289,846 230,831 Current assets Debtors 441 5,191 4,399 Cash at bank 5,458 1,971 7,050 Derivative (options) - financial - 83 - investments 5,899 7,245 11,449 Creditors Amounts falling due within one year (45,796) (28,704) (17,035) Derivative (options) - financial (748) - (462) investments (46,544) (28,704) (17,497) Net current liabilities (40,645) (21,459) (6,048) Total net assets 254,695 268,387 224,783 Capital and reserves Called up share capital 11,105 13,459 11,772 Share premium account 117,706 117,639 117,639 Warrant reserve 7,417 7,426 7,426 Capital reserves 112,192 126,282 81,611 Capital redemption reserve 3,678 1,321 3,008 Revenue reserve 2,597 2,260 3,327 Total equity shareholders' funds 254,695 268,387 224,783 Net asset value per share - basic 584.1p 551.7p 486.6p (note 5) Net asset value per share - diluted 560.3p 535.9p 482.4p (note 5) Cash Flow Statement For the six months ended 30 September 2008 (Unaudited) (Unaudited) (Audited) Six months Six months Year ended ended ended 30 September 30 September 31 March 2008 2007 2008 £'000 £'000 £'000 Net cash outflow from operating (210) (432) (332) activities Servicing of finance Interest paid (168) (644) (1,023) Taxation 24 135 124 Taxation recovered Financial investment Purchases of investments (143,872) (98,888) (219,443) Sales of investments 132,902 119,927 269,680 Net cash (outflow)/inflow from (10,970) 21,039 50,237 financial investment Equity dividends paid (1,344) (1,544) (1,544) Net cash (outflow)/inflow before (12,668) 18,554 47,462 financing Financing Shares issued from exercise of 61 68 68 warrants Purchase of shares (13,236) (19,382) (30,618) Increase/(decrease) in short term 24,725 2,098 (10,308) loans Net cash inflow/ (outflow) from 11,550 (17,216) (40,858) financing (Decrease)/increase in cash in the (1,118) 1,338 6,604 period Notes to the Financial Statements 1. Accounting Policies The condensed financial statements have been prepared under the historical cost convention, modified to include the valuation of investments at fair value and in accordance with United Kingdom Generally Accepted Accounting Practice and with the Statement of Recommended Practice `Financial Statements of Investment Trust Companies' dated December 2005. All of the Company's operations are of a continuing nature. The same accounting policies used for the year ended 31 March 2008 have been applied. 2. Income (Unaudited) (Unaudited) (Audited) Six months ended Six months ended Year ended 30 September 30 September 31 March 2008 2007 2008 £'000 £'000 £'000 Investment income 1,149 1,152 3,032 Interest receivable 59 211 372 Total 1,208 1,363 3,404 3. Investment Management and Management Fees (Unaudited) (Unaudited) (Audited) Six months ended Six months ended Year ended 30 September 30 September 31 March 2008 2007 2008 £'000 £'000 £'000 Investment management and management fees 1,107 1,309 2,445 Total 1,107 1,309 2,445 Notes to the Financial Statements (continued) 4. Return/(Loss) per Share (Unaudited) (Unaudited) (Audited) Six months Six months Year ended ended 30 ended 30 September 2008 September 2007 31 March 2008 £'000 £'000 £'000 The return/(loss) per share is based on the following figures: Revenue return 614 674 1,741 Capital return/(loss) 43,163 14,633 (18,261) Total return/(loss) 43,777 15,307 (16,520) Weighted average number of 44,783,068 50,710,624 49,231,108 shares in issue for the period/ year - basic Revenue return per share 1.4p 1.3p 3.5p Capital return/(loss) per share 96.4p 28.9p (37.1)p Total return/(loss) per share 97.8p 30.2p (33.6)p Weighted average number of 45,332,435 51,325,484 49,675,682 shares in issue for the period - diluted Revenue return per share 1.4p 1.3p *3.5p Capital return/(loss) per share 95.2p 28.5p *(37.1)p Total return/(loss) per share - 96.6p 29.8p *(33.6)p diluted * dilution not applicable 5. Net Asset Value per Share and Issued Share Capital Net asset value per share is calculated on attributable assets at 30 September 2008 of £254,695,000 (30 September 2007: £268,387,000 and 31 March 2008: £ 224,783,000) and 43,607,481 being the number of shares in issue at 30 September 2008 (30 September 2007: 48,643,468 and 31 March 2008: 46,190,161). The diluted net asset value per share assumes all 10,745,610 outstanding warrants are exercised at 464p per share resulting in assets attributable to equity shareholders of £304,555,000 (30 September 2007: £318,307,000, 31 March 2008: 274,703,000) and on the resultant number of shares of 54,353,091 (30 September 2007: 59,402,148, 31 March 2008: 56,948,841). Notes to the Financial Statements (continued) 6. Transaction Costs Purchase transaction costs for the six months ended 30 September 2008 were £ 161,000 (six months ended 30 September 2007: £165,000; year ended 31 March 2008: £349,000). Sales transaction costs for the six months ended 30 September 2008 were £ 168,000 (six months ended 30 September 2007: £218,000; year ended 31 March 2008: £395,000). 7. Publication of Non Statutory Accounts The financial information contained in this preliminary announcement does not constitute statutory accounts as defined in section 240 of the Companies Act 1985. The financial information for the half years ended 30 September 2008 and 30 September 2007 has not been audited or reviewed by the auditors. The information for the year ended 31 March 2008 has been extracted from the latest published audited financial statements. The audited financial statements for the year ended 31 March 2008 have been filed with the Registrar of Companies. The report of the auditors on those accounts was unqualified, did not include a reference to any matters to which the auditors drew attention by way of emphasis without qualifying the report, and did not contain statements under section 237(2) or 237(3) of the Companies Act 1985.
UK 100

Latest directors dealings