510K Clearance

Advanced Medical Solutions Grp PLC 11 October 2006 For immediate release 11 October 2006 Advanced Medical Solutions Group plc ('AMS' or 'the Company') FDA clears surgical skin sealant for sale in US Winsford, UK: Advanced Medical Solutions Group plc (AIM: AMS), the global medical technology company, today announces that Kimberly-Clark* Integuseal* Microbial Sealant has received 510(k) clearance by the Food & Drug Administration (FDA) allowing it to be marketed in the US. Kimberly-Clark* Integuseal* Microbial Sealant is used to reduce the risk of skin flora contamination throughout a surgical procedure, a key factor in the development of surgical site infections which occur in 2-5% of all surgical procedures. This can lead to serious complications and increased morbidity to the patient and significant incremental costs to health care providers. It is generally accepted that contamination by the patient's endogenous skin flora is a key factor in the development of surgical site infections and despite standard preventative steps, these remain an issue of concern. Based upon patented cyanoacrylate technology, AMS has developed an innovative film-forming solution that bonds to the skin sealing off the spaces where bacteria can grow and immobilises endogenous pathogens thereby reducing the risk of skin flora contamination. A novel applicator has been developed that allows the solution to be effectively applied even on irregular and contoured areas of the body, such as shoulders and knees, which are generally difficult to drape. Easy to apply and fast-drying, Kimberly-Clark* Integuseal* Microbial Sealant can be used in conjunction with a variety of preparatory treatments and surgical products such as electrocautery, sutures, staples and wound adhesives. In March 2006 AMS announced that it had entered into a strategic partnership with Kimberly-Clark Health Care who would have exclusive rights to market and distribute this technology in all global markets under its brand Kimberly-Clark* Integuseal* Microbial Sealant. Atlanta based Kimberly-Clark Health Care is an over $1 billion turnover business unit within the global Kimberly-Clark Corporation. It manufactures and markets a wide range of surgical products and is a leader in several medical device categories. Commenting on today's announcement Dr. Don Evans, Chief Executive of AMS stated: 'We are delighted that Kimberly-Clark* Integuseal* Microbial Sealant has now been cleared for sale into the US. The product has already been cleared and launched into the EU and other geographies and this allows entry into the world's biggest market during 2007. 'Kimberly-Clark Health Care's strong presence and focus on infection control in the Operating Room make it an ideal partner for rapid commercialisation of this exciting new technology.' -ENDS- For further information, please contact: Advanced Medical Solutions Group plc Tel : +44 (0) 1606 545508 Don Evans, Chief Executive Mary Tavener, Finance Director www.admedsol.com Buchanan Communications Tel: +44 (0) 20 7466 5000 Mark Court, Mary-Jane Johnson Notes to Editors: Advanced Medical Solutions is a leading company in the development and manufacture of products for the $13 billion global woundcare market. Founded in 1991 and currently quoted on AIM, Advanced Medical Solutions is focused on the design, development and manufacture of innovative and technologically advanced products for woundcare and other medical applications. In-house natural and synthetic polymer technology is used to provide advanced wound dressings based on the moist healing principle. AMS's resources ensure a unique position as a vertically integrated 'one stop shop' to provide all categories of moist wound healing products. The Company has the capability to move from product design and development through to production and delivery ready for distribution into customer markets. The acquisition of MedLogic in 2002 has brought AMS products and technology in cyanoacrylate based tissue adhesives that offer benefits over sutures and staples for closing wounds sold direct to hospitals or through distributors. AMS's technology and products currently serve the majority of the key global markets and strategic partners. Kimberly-Clark in the Healthcare Environment Around the world, medical professionals turn to Kimberly-Clark for a wide portfolio of solutions that improve the health, hygiene and well-being of their patients and staff. As part of their healing mission, caregivers rely on Kimberly-Clark to deliver clinical solutions and educational resources that they can depend on to prevent, diagnose and manage a wide variety of healthcare-associated infections. This over $1 billion global enterprise of Kimberly-Clark Corporation holds the No. 1 and No. 2 market share positions in several categories including infection control solutions, surgical solutions, pain management and digestive health. And throughout the care continuum, patients and staff alike trust Kimberly-Clark* medical supplies and devices, KLEENEX* tissues, KIMBERLY-CLARK* professional skin care products, and SCOTT* towels for day-to-day needs. For more information, please visit http://www.kchealthcare.com. * Registered Trademark or Trademark of Kimberly-Clark Worldwide, Inc. (c) 2006 KCWW. This information is provided by RNS The company news service from the London Stock Exchange
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