Holding(s) in Company

Advanced Medical Solutions Grp PLC
16 April 2007


TR-1:               Notification of major interests in shares

1. Identity of the issuer or the underlying issuer of     Advanced Medical Solutions Group Plc
existing shares to which voting rights are attached

2. Reason for the notification     (please tick the appropriate box or boxes)

An acquisition or disposal of voting rights                        X

An acquisition or disposal of financial instruments which may result in the
acquisition of shares already issued to which voting rights are attached

An event changing the breakdown of voting rights

Other (please specify): Initial notification of shareholding under Transparency
Directive

3. Full name of person(s) subject to the                         AMVESCAP PLC
notification obligation:

4. Full name of shareholder(s) (if different                     AMVESCAP PLC
from 3.):

5. Date of the transaction (and date on which                      12/04/07
the threshold is crossed or reached if
different):

6. Date on which issuer notified:                                  13/04/07

7. Threshold(s) that is/are crossed or reached:                               10%

8. Notified details:

A: Voting rights attached to shares
Class/type of    Situation previous to the   Resulting situation after the triggering transaction(i)
shares           Triggering transaction

 if possible     Number of     Number of     Number of    Number of voting       % of voting rights
using the ISIN   Shares        Voting Rights shares       rights
CODE
                                                          Direct    Indirect     Direct    Indirect

GB0004536594     14,574,938    14,574,938    14,014,938             14,014,938             9.86%


B: Financial Instruments
Resulting situation after the triggering transactio
Type of financial     Expiration date Exercise/ Conversion      Number of voting rights    % of
instrument                            Period/ Date              that may be acquired if    voting
                                                                the instrument is          rights
                                                                exercised/ converted.
          -


Total (A+B)
Number of voting rights                             % of voting rights
14,014,938                                          9.86%


9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively
held, if applicable:

Chase Nominees - 7,345,659

Vidacos Nominees - 6,669,279




Proxy Voting:

10. Name of the proxy holder:                                  na

11. Number of voting rights proxy holder will cease to hold:   na

12. Date on which proxy holder will cease to hold voting       na
rights:

13. Additional information:

14. Contact name:                           Mary Tavener

15. Contact telephone number:               44 (0)1606 545509




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