Holding(s) in Company

Advanced Medical Solutions Grp PLC
10 July 2007


TR-1:               notification of major interests in shares

1. Identity of the issuer or the underlying issuer of     Advanced Medical Solutions Group Plc
existing shares to which voting rights are attached

2. Reason for the notification     (please tick the appropriate box or boxes)

An acquisition or disposal of voting rights                                 X

An acquisition or disposal of financial instruments which may result in the
acquisition of shares already issued to which voting rights are attached

An event changing the breakdown of voting rights
Other (please specify): Initial notification of shareholding under Transparency
Directive

3. Full name of person(s) subject to the           Newton Investment Management Limited
notification obligation:

4. Full name of shareholder(s) (if different       Newton Investment Management Limited
from 3.):

5. Date of the transaction (and date on which                      06/07/07
the threshold is crossed or reached if
different):

6. Date on which issuer notified:                                  09/07/07

7. Threshold(s) that is/are crossed or reached:                 Reduction from 10.59% to 9.54%

8. Notified details:                                                 Sale 1,500,000 shares


A: Voting rights attached to shares
Class/type of     Situation previous to   Resulting situation after the triggering transaction(i)
shares            the Triggering
                  transaction
 if possible      Number of    Number of  Number of       Number of voting rights % of voting rights
using the ISIN    Shares       Voting     shares
CODE                           Rights                     Direct      Indirect    Direct    Indirect

GB0004536594      15,137,657   10.59%     N/A             N/A         13,637,657  N/A       9.54%
(Ordinary Shares)


B: Financial Instruments
Resulting situation after the triggering transactio
Type of financial     Expiration date Exercise/ Conversion      Number of voting rights    % of
instrument                            Period/ Date              that may be acquired if    voting
                                                                the instrument is          rights
                                                                exercised/ converted.



Total (A+B)

Number of voting rights                             % of voting rights

13,637,657                                          9.54%


9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively
held, if applicable:

Newton Investment Management Ltd hold these shares as discretionary Investment Manager


Proxy Voting:

10. Name of the proxy holder:                                  N/A

11. Number of voting rights proxy holder will cease to hold:   N/A

12. Date on which proxy holder will cease to hold voting       N/A
rights:

13. Additional information:

14. Contact name:                           Mary Tavener

15. Contact telephone number:               [phone]




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