Holding(s) in Company

Advanced Medical Solutions Grp PLC
30 April 2007


TR-1:               NOTIFICATION OF MAJOR INTERESTS IN SHARES 

1. Identity of the issuer or the underlying issuer of     Advanced Medical Solutions Group Plc
existing shares to which voting rights are attached

2. Reason for the notification     (please tick the appropriate box or boxes)

An acquisition or disposal of voting rights                                               x

An acquisition or disposal of financial instruments which may result in the
acquisition of shares already issued to which voting rights are attached

An event changing the breakdown of voting rights

Other (please specify): Initial notification of shareholding under Transparency
Directive

3. Full name of person(s) subject to the       AXA S.A., 25 Avenue Matignon, 75008 Paris and its
notification obligation:                                    group of companies

4. Full name of shareholder(s) (if different
from 3.):

5. Date of the transaction (and date on which                    29 April 2007
the threshold is crossed or reached if
different):

6. Date on which issuer notified:                                30 April 2007

7. Threshold(s) that is/are crossed or reached:                  12%

8. Notified details:


A: Voting rights attached to shares
Class/type of     Situation previous to   Resulting situation after the triggering transaction(i)
shares            the Triggering
                  transaction
 if possible      Number of   Number of   Number of       Number of voting rights % of voting rights
using the ISIN    Shares      Voting      shares
CODE                          Rights                      Direct      Indirect    Direct    Indirect

GB0004536594      16,937,661  16,937,661  215,161         215,161     16,922,500  0.15      11.85


B: Financial Instruments
Resulting situation after the triggering transactio
Type of financial     Expiration date Exercise/ Conversion      Number of voting rights    % of
instrument                            Period/ Date              that may be acquired if    voting
                                                                the instrument is          rights
                                                                exercised/ converted.
          -


Total (A+B)
Number of voting rights                             % of voting rights

17,137,661                                          12.00%


9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively
held, if applicable:


Name of Company / Fund                                             Number of Shares    % of issued share capital

Sun Life Pensions Management Ltd                                             15,161     0.01062%
Direct

Sun Life Pensions Management Ltd                                            200,000     0.14009%
Direct

AXA Framlington Framlington Innovative Growth                            10,000,000     7.00450%
Indirect

AXA Framlington Biotech                                                   2,550,000     1.78615%
Indirect

Framlington onshore private clients                                       2,172,500     1.52173%
Indirect

AWF Framlington Health                                                    2,200,000     1.54099%
Indirect

Total Direct                                                                215,161     0.15071%

Total Indirect                                                           16,922,500    11.85336%

TOTAL                                                                    17,137,661    12.00407%


Proxy Voting:

10. Name of the proxy holder:

11. Number of voting rights proxy holder will cease to hold:

12. Date on which proxy holder will cease to hold voting
rights:

13. Additional information:

14. Contact name:                           Mary Tavener

15. Contact telephone number:               [phone]




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