Holding(s) in Company

Advanced Medical Solutions Grp PLC
21 May 2007


TR-1:               Notification of major interests in shares

1. Identity of the issuer or the underlying issuer of     Advanced Medical Solutions Group Plc
existing shares to which voting rights are attached


2. Reason for the notification     (please tick the appropriate box or boxes)

An acquisition or disposal of voting rights                                    x

An acquisition or disposal of financial instruments which may result in the
acquisition of shares already issued to which voting rights are attached

An event changing the breakdown of voting rights

Other (please specify):


3. Full name of person(s) subject to the       AXA S.A., 25 Avenue Matignon, 75008 Paris and its
notification obligation:                                    group of companies


4. Full name of shareholder(s) (if different
from 3.):


5. Date of the transaction (and date on which                     16 May 2007
the threshold is crossed or reached if
different):


6. Date on which issuer notified:                                 18 May 2007


7. Threshold(s) that is/are crossed or reached:                        12%


8. Notified details:


A: Voting rights attached to shares

Class/type of     Situation previous to   Resulting situation after the triggering transaction(i)
shares            the Triggering
                  transaction

 if possible      Number of   Number of   Number of       Number of voting rights % of voting rights
using the ISIN    Shares      Voting      shares
CODE                          Rights                      Direct      Indirect    Direct    Indirect

GB0004536594      17,162,661  17,162,661  315,161         315,161     17,197,500  0.22      12.05


B: Financial Instruments

Resulting situation after the triggering transactio

Type of financial     Expiration date Exercise/ Conversion      Number of voting rights    % of
instrument                            Period/ Date              that may be acquired if    voting
                                                                the instrument is          rights
                                                                exercised/ converted.
          -


Total (A+B)

Number of voting rights                             % of voting rights

17,512,661                                          12.27%


9. Chain of controlled undertakings through which the voting rights and/or the
financial instruments are effectively held, if applicable:


Name of Company / Fund                                       Number of Shares         % of issued share capital


Sun Life Pensions Management Ltd                                       15,161                      0.01062%
Direct


Sun Life Pensions Management Ltd                                      300,000                      0.21013%
Direct



AXA Framlington Framlington Innovative Growth                      10,000,000                      7.00450%
 Indirect



AXA Framlington Health                                              1,000,000                      0.70045%
Indirect



AXA Framlington Biotech                                             2,550,000                      1.78615%
Indirect



Framlington onshore private clients                                 2,447,500                      1.71435%
Indirect



AWF Framlington Health                                              1,200,000                      0.84054%
Indirect




Total Direct                                                          315,161                      0.22075%
Total Indirect                                                     17,197,500                     12.04598%



TOTAL                                                              17,512,661                     12.26674%



Proxy Voting:

10. Name of the proxy holder:

11. Number of voting rights proxy holder will cease to hold:

12. Date on which proxy holder will cease to hold voting
rights:

13. Additional information:

14. Contact name:                           Mary Tavener

15. Contact telephone number:               [phone]




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