Holding(s) in Company

Advanced Medical Solutions Grp PLC
09 March 2007


TR-1:               Notification of major interests in shares


1. Identity of the issuer or the underlying issuer of     Advanced Medical Solutions Group Plc
existing shares to which voting rights are attached

2. Reason for the notification     (please tick the appropriate box or boxes)

An acquisition or disposal of voting rights

An acquisition or disposal of financial instruments which may result in the
acquisition of shares already issued to which voting rights are attached

An event changing the breakdown of voting rights

Other (please specify): Initial notification of shareholding under Transparency           X
Directive

3. Full name of person(s) subject to the                       Barclays PLC
notification obligation:

4. Full name of shareholder(s) (if different           Barclays Stockbrokers Limited
from 3.):

5. Date of the transaction (and date on which                    5 March 2007
the threshold is crossed or reached if
different):

6. Date on which issuer notified:                                7 March 2007

7. Threshold(s) that is/are crossed or reached:                               n/a

8. Notified details:


A: Voting rights attached to shares

Class/type of     Situation previous to   Resulting situation after the triggering transaction(i)
shares            the Triggering
                  transaction
 if possible      Number of   Number of   Number of       Number of voting rights % of voting rights
using the ISIN    Shares      Voting      shares
CODE                          Rights                      Direct      Indirect    Direct    Indirect
GB0004536594      9,132,291   9,132,291   9,140,671                   9,140,671             6.43%


B: Financial Instruments
Resulting situation after the triggering transactio
Type of financial     Expiration date Exercise/ Conversion      Number of voting rights    % of
instrument                            Period/ Date              that may be acquired if    voting
                                                                the instrument is          rights
                                                                exercised/ converted.
          -


Total (A+B)
Number of voting rights                             % of voting rights
9,140,671                                           6.43%


9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively
held, if applicable:


Barclays Stockbrokers Limited




Proxy Voting:

10. Name of the proxy holder:

11. Number of voting rights proxy holder will cease to hold:

12. Date on which proxy holder will cease to hold voting
    rights:

13. Additional information:

14. Contact name:                           Mary Tavener

15. Contact telephone number:               44 (0)1606 545509




--------------------------





                      This information is provided by RNS
            The company news service from the London Stock Exchange