Holding(s) in Company

Advanced Medical Solutions Grp PLC
16 March 2007


TR-1:               NOTIFICATION OF MAJOR INTERESTS IN SHARES 

1. Identity of the issuer or the underlying issuer of     Advanced Medical Solutions Group Plc
existing shares to which voting rights are attached
2. Reason for the notification     (please tick the appropriate box or boxes)
An acquisition or disposal of voting rights                                               x
An acquisition or disposal of financial instruments which may result in the
acquisition of shares already issued to which voting rights are attached
An event changing the breakdown of voting rights
Other (please specify): Initial notification of shareholding under Transparency
Directive
3. Full name of person(s) subject to the                         AXA S.A.
notification obligation:
4. Full name of shareholder(s) (if different
from 3.):
5. Date of the transaction (and date on which                    2 March 2007
the threshold is crossed or reached if
different):
6. Date on which issuer notified:                                15 March 2007
7. Threshold(s) that is/are crossed or reached:                               n/a
8. Notified details:


A: Voting rights attached to shares
Class/type of     Situation previous to   Resulting situation after the triggering transaction(i)
shares            the Triggering
                  transaction
 if possible      Number of   Number of   Number of       Number of voting rights % of voting rights
using the ISIN    Shares      Voting      shares
CODE                          Rights                      Direct      Indirect    Direct    Indirect
GB0004536594                              165,161         165,161     16,772,500  0.12%     11.8%


B: Financial Instruments
Resulting situation after the triggering transactio
Type of financial     Expiration date Exercise/ Conversion      Number of voting rights    % of
instrument                            Period/ Date              that may be acquired if    voting
                                                                the instrument is          rights
                                                                exercised/ converted.
          -


Total (A+B)
Number of voting rights                             % of voting rights
16,937,661                                          11.92%


9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively
held, if applicable:


Sun Life Pensions Management                     15,161                  0.01067

Sun Life Pensions Management                     150,000                 0.10557

AXA Framlington Framlington Innovation Growth 10,000,000                 7.03816

AXA Framlington Biotech                        2,550,000                 1.79473

Framlington onshore private clients            2,022,500                 1.42347

LWFFFH                                         2,200,000                 1.54840




Proxy Voting:
10. Name of the proxy holder:
11. Number of voting rights proxy holder will cease to hold:
12. Date on which proxy holder will cease to hold voting
rights:
13. Additional information:
14. Contact name:                           Mary Tavener
15. Contact telephone number:               44 (0)1606 545509




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