New Agreement

Advanced Medical Solutions Grp PLC 30 April 2004 For immediate release 30 April 2004 Advanced Medical Solutions Group plc Announces distribution deal for use of super-glue for closing surgical wounds in Orthopaedics Winsford, UK: Advanced Medical Solutions (AIM: AMS), the global woundcare technology company, today announces that it has entered into an agreement with Endo Plus UK Ltd for marketing and distribution of its LiquiBand SurgicalTM product for orthopaedic use in the UK. LiquiBand SurgicalTM is a novel medical device that utilises super glue technology for closing surgical incisions in the operating theatre and provides benefits over conventional techniques such as suturing and stapling. This technology has already proven to be very successful for wound closure in Accident and Emergency (A&E) departments, where AMS' MedLogic division is market leader in the UK. The new LiquiBand SurgicalTM product has been designed to meet the requirements of the surgeon, nursing staff and patient. It consists of a two-part system - a fast setting, high strength adhesive is used to close the incision and then a liquid adhesive film is painted over the skin. This sets to provide a post-operative dressing that is secure, flexible and resistant to water and bacteria. This form of closure also helps to minimise scarring after surgery thus providing a good cosmetic result for the patient. The global market for wound closure is estimated at more than $3 billion, of which tissue adhesives are a rapidly growing segment. It has been estimated that up to 40 per cent of wounds currently closed by sutures and staples are suitable for adhesives. Although these products are becoming routinely used in many A&E departments, the major market opportunity for them is for closing surgical incisions in the operating theatre. The new LiquiBand SurgicalTM product, which was approved for sale throughout Europe in December 2003, has been introduced into the UK by the MedLogic direct sales team and is also being rolled out throughout Europe using new and existing distributors that have a good understanding of the surgical wound closure market, a presence in the operating theatre and a willingness to focus on new, innovative products. The initial response to the product from surgeons has been extremely positive with successful closures ranging from small keyhole incisions to major wounds. A particular area of interest is in orthopaedic surgery where the product offers benefits over sutures and staples for closing incisions after joint replacement. By partnering with Endo Plus, AMS believes it can achieve strong sales support for the product in this particular area. Endo Plus UK, which has a sales team of 10 covering the UK orthopaedic surgeon community, manufactures and distributes a wide range of hip and knee replacement products. It is ideally placed to support the introduction of LiquiBand SurgicalTM for use in orthopaedic surgery. Commenting on this announcement Dr Don Evans, CEO of AMS, stated: 'Our early experiences with LiquiBand SurgicalTM confirm that this is a very exciting product that can offer real benefits to surgeons, post-operative nursing staff and patients compared with conventional methods of wound closure. 'With its strong presence and relationships with orthopaedic surgeons and theatre staff in the UK I believe that Endo Plus is ideally placed to deliver success with this product.' Mr Phil Davies, Managing Director of Endo Plus, added: 'We are always very interested in products that add value to our current range. Initial clinical evaluations have demonstrated that LiquiBand SurgicalTM is an excellent product for closure of orthopaedic surgical wounds and we look forward to expanding its usage in this area throughout the UK. 'There is the potential for this product to revolutionise the way surgical wounds are closed. Eliminating the need for the removal of sutures or staples is very good news for both hospitals and patients.' - ENDS - For further information, please contact: Advanced Medical Solutions Group plc Tel : +44 (0) 1606 545508 Don Evans, Chief Executive Mary Tavener, Finance Director www.admedsol.com ------------------ Buchanan Communications Tel: +44 (0) 20 7466 5000 Mark Court, Mary-Jane Johnson Notes to Editors: Advanced Medical Solutions is a leading company in the development and manufacture of products for the $15 billion global woundcare market. Founded in 1991 and currently quoted on AIM, Advanced Medical Solutions is focused on the design, development and manufacture of innovative and technologically advanced products for woundcare and other medical applications. In-house natural and synthetic polymer technology is used to provide advanced wound dressings based on the moist healing principle. AMS's resources ensure a unique position as a vertically integrated 'one stop shop' to provide all categories of moist wound healing products. The Company has the capability to move from product design and development through to production and delivery ready for distribution into customer markets. The acquisition of MedLogic in 2002 has brought AMS products and technology in cyanoacrylate based tissue adhesives and sealants sold direct to hospitals or through distributors. AMS's technology and products currently serve the majority of the key global markets with strategic partners including 3M, Novartis, Johnson & Johnson, Molnlycke Healthcare, Coloplast, Smith & Nephew and Beiersdorf. This information is provided by RNS The company news service from the London Stock Exchange
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