Notifiable Interest

Advanced Medical Solutions Grp PLC 05 September 2007 TR-1: Notifications of Major Interests in Shares Advanced Medical Solutions 1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached: 2. Reason for notification (yes/no) Yes An acquisition or disposal of voting rights An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached An event changing the breakdown of voting rights Other (please specify): 3. Full name of person(s) subject to notification obligation: Newton Investment Management Limited 4. Full name of shareholder(s) (if different from 3): 5. Date of transaction (and date on which the threshold is crossed or reached if different): 04/09/07 6. Date on which issuer notified: 05/09/07 7. Threshold(s) that is/are crossed or reached: Decrease from 7.66% to 6.96% 8: Notified Details Sale of 1,000,000 shares A: Voting rights attached to shares Class/type of Situation previous to Resulting situation after the triggering transaction shares the triggering transaction If possible use Number of Number of Number of Number of voting rights Percentage of voting ISIN code shares voting shares rights rights Direct Indirect Direct Indirect Ordinary shares 10,947,657 10,947,657 N/A N/A 9,947,657 N/A 6.96 GB0004536594 B: Financial Instruments Resulting situation after the triggering transaction Type of financial Expiration date Exercise/ conversion No. of voting rights Percentage of voting instrument period/date that may be acquired rights (if the instrument exercised/converted) Total (A+B) Number of voting rights Percentage of voting rights 9,947,657 6.96% 9. Chain of controlled undertakings through which the voting rights and /or the financial instruments are effectively held, if applicable: Newton Investment Management Limited hold these shares as a discretionary Investment Manager. Proxy Voting: 10. Name of proxy holder: N/A 11. Number of voting rights proxy holder will cease N/A to hold: 12. Date on which proxy holder will cease to hold N/A voting rights: 13. Additional information: 14 Contact name: Mary Tavener 15. Contact telephone name: +44 (0) 1606 545509 This information is provided by RNS The company news service from the London Stock Exchange
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