Re Directorate

Advanced Medical Solutions Grp PLC
16 January 2001


                     ADVANCED MEDICAL SOLUTIONS GROUP PLC
                                 BOARD CHANGES
                                       
Advanced  Medical  Solutions Group plc. announced  today  the  appointment  of
Geoffrey Vernon as Non-Executive Chairman with immediate effect.

This  appointment represents a smooth transition from outgoing Chairman  James
Noble  who is taking up a full time CEO role at Avidex, which requires him  to
relinquish a number of his Non-Executive positions.

Geoffrey has been a Non-Executive Director of Advanced Medical Solutions since
1998  and  was  a  venture  capitalist with Advent Ltd  and  Rothschild  Asset
Management.   He is currently Non-Executive Chairman of XTL Biopharmaceuticals
plc and has been involved at Board level in a number of successful turnarounds
and venture capital investments such as Oxford Glycosciences plc and Morphosys
Ag.

In a further move to strengthen the Board, Stephen Harris has been appointed a
Non-Executive  Director of the Company. Steve's career has been  in  both  the
prescription  and  consumer  healthcare sectors,  with  sales,  marketing  and
general  management  experience with MSD, Lilly, Boots and  Reckitt  &  Colman
before  becoming a main Board Director of Medeva plc.  Steve  now  holds  Non-
Executive  positions at SkyePharma plc, Proteome Sciences plc,  Pharmaceutical
Profiles Limited, Microscience Limited and Trigen Limited.



James Noble, outgoing Non-Executive Chairman commented:

'I  have enjoyed my association with Advanced Medical Solutions and am pleased
to have contributed to the clear progress that is being made.

'I  am  confident that the management team has now turned the corner and under
Geoffrey's  Chairmanship will continue to build on this  success  and  enhance
value for shareholders'.


Geoffrey Vernon, new Non-Executive Chairman added:
'I  am delighted to be assuming the role of Chairman at this exciting time for
the  company. I look forward to working with Don Evans and the Executive  team
to  maintain  the progress we have made to date in transitioning  the  Company
towards higher value-added products.'


Commenting on the appointments, Don Evans, Chief Executive said:

'We  are pleased to welcome Geoffrey and Steve into their new positions on the
Board  and  look forward to working with them. I would also like to take  this
opportunity to thank James for his invaluable contribution to the Company over
the past three years.

'The  business  continues to grow and we are on track to meet expectations  in
terms  of reducing our losses and cash outflow.  We remain confident  that  we
can   further   develop  the  business  and  maintain  our  progress   towards
profitability.'

There are no disclosures in respect of Steve Harris, which require to be  made
under  paragraph  6F2  (b)  to (g) of the Listing  Rules  of  the  UK  Listing
Authority.


This news release contains forward-looking statements that reflect the
Company's current expectation regarding future events.  Forward-looking
statements involve risks and uncertainties.  Actual events could differ
materially from those projected herein and depend on a number of factors
including the uncertainties relating to the development of new medicines and
the regulatory process.

For press enquiries please contact:

Advanced Medical Solutions Group plc              Tel: [phone]
Don Evans, Chief Executive
Mary Tavener, Finance Director
www.admedsol.com

Gavin Anderson & Company                          Tel: [phone]
Philip Ward / Charlotte Stone