Holding(s) in Company

Allergy Therapeutics PLC 27 February 2007 TR-1: notification of major interests in shares 1. Identity of the issuer or the underlying issuer of existing Allergy Therapeutics plc shares to which voting rights are attached: 2. Reason for the notification (please tick the appropriate box or boxes): An acquisition or disposal of voting rights An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached An event changing the breakdown of voting rights X 3. Full name of person(s) subject to the notification Fidelity International Limited (FIL) obligation: 4. Full name of shareholder(s) (if different from 3.): See 8 below 5. Date of the transaction and date on which the threshold is Revised reporting obligation under the crossed or reached: Discolsure and Transparency Rules (DTR) 6. Date on which issuer notified: 23/02/07 7. Notified details: A: Voting rights attached to shares Class/type of shares Situation previous Resulting situation after the triggering transaction to the Triggering if possible using the transaction ISIN CODE Number of Number of Number of Number of voting rights % of voting rights Shares Voting shares Rights Direct Direct Indirect Direct Indirect GB00B02LCQ05 11,589,930 11,589,930 14.14% B: Financial Instruments Resulting situation after the triggering transaction Type of financial Expiration date Exercise/ Conversion Number of voting rights % of voting instrument Period/ Date that may be acquired if rights the instrument is exercised/ converted Total (A+B) Number of voting rights % of voting rights 11,589,930 14.14 8. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable: Fidelity International Limited (FIL) is the parent holding company for various direct and indirect subsidiaries, including Fidelity Fund Management Limited (FFML), Fidelity Investment Services Ltd (FISL), Fideilty Gestion (FIGEST), Fideilty Investments Advisory (Korea) Limited (FIAKL), Fidelity Investments Management (Hong Kong) Limited (FIMHK), Fidelity Pension Management (FPM), Fidelity Investments Japan (FIJ) and Fidelity Investments International (FII), investment managers for various non-US investment companies and institutional clients. UK Nominee Management Company Shares Held State Str Bk and Tr Co LNDN FPM 635,784 Northern Trust London FPM 602,000 Midland Securities Services FPM 174,300 Mellon Bank FPM 684,400 JP Morgan, Bournemouth FPM 947,136 JP Morgan, Bournemouth FISL 5,724,798 JP Morgan, Bournemouth FIL 1,501,512 Brown Bros Harrimn Ltd Lux FIL 861,000 Bank of New York, Brussels FPM 459,000 Total 11,589,930 Proxy Voting: 9. Name of the proxy holder: Fidelity International Limited (FIL) 10. Number of voting rights proxy holder will cease to hold: N/A 11. Date on which proxy holder will cease to hold voting rights: N/A 12. Additional information: In accordance with the reporting requirements of the DTR Fideilty Investments International will now report the indirect holdings of Fidelity International Limited and FMR Corp seperately. For this purpose FMR Corp has nil holdings in Allergy Therapeutics plc This information is provided by RNS The company news service from the London Stock Exchange
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