Director of Share Purchase

Alliance Pharma PLC
04 October 2007


For Immediate Release                                       4 October 2007


                              ALLIANCE PHARMA PLC
                         ('Alliance' or 'the Company')

                            Director Share Purchase

Alliance Pharma plc (AIM: APH), the speciality pharmaceutical company, announces
that Andrew Smith, a non-executive director, yesterday made a purchase of
100,000 ordinary shares of 1p each in the Company at a price of 8.85p.

This brings Mr Smith's total holding to 160,000 shares, representing 0.099% of
the issued share capital of Alliance Pharma plc.


For further information:

Alliance Pharma plc                                   + 44 (0) 1249 466966
John Dawson, Chief Executive

Richard Wright, Finance Director
www.alliancepharma.co.uk

Numis Securities                                     + 44 (0) 20 7260 1000
David Poutney
Michael Meade

Buchanan Communications                              + 44 (0) 20 7466 5000
Mark Court
Rebecca Skye Dietrich


Notes to editors

About Alliance Pharma

Alliance Pharma, founded in 1996, is an AIM listed speciality pharmaceutical
company based in Chippenham, Wiltshire, UK. The company has a strong track
record of acquiring the rights to established niche brands and owns, or shares,
the rights to 34 branded pharmaceutical products.

Alliance Pharma's products are prescribed in the treatment of a wide range of
conditions and include brands used in periodontitis (a serious gum disease), the
prevention of heart disease, in Parkinson's disease, in nutrition, in nasal
infections, in the treatment of dermatological conditions and in childbirth.
Alliance Pharma's sales are mainly prescription driven. Its products are
distributed to hospitals directly and to pharmaceutical wholesalers which
service both hospital and retail pharmacies with their prescription
requirements.

Alliance Pharma joined the AIM market of the London Stock Exchange in December
2003 and trades under the symbol APH.




                      This information is provided by RNS
            The company news service from the London Stock Exchange