Holding(s) in Company

Alliance Pharma PLC
30 March 2005

For immediate release: 30 March  2005





                              ALLIANCE PHARMA PLC

                         ('Alliance' or 'the Company')


                            SHAREHOLDINGS IN COMPANY



           Fidelity acquire an additional  3,700,000 ordinary shares





On 30th March 2005 the Company was notified by Fidelity Investments, ('FMR Corp
'), that it had increased its shareholding by 3,700,000 shares. The notifiable
interest is with FMR Corp and Fidelity International Limited (FIL) which also
comprises the notifiable interest of Mr Edward C Johnson 3d, a principal
shareholder of FMR Corp and Fidelity International Limited. The shares held
currently are as follows:


       Shares Held       Management Company     Nominee/Registered Name
           240,500       FIL                    Brown Brothers Harriman Ltd LUX
         9,959,500       FMRCO                  Mellon Bank
  TOTAL 10,200,000



The total percentage shareholding of FMR Corp and Fidelity International Limited
is now 9.43%



On 30th March 2005, the Company was also notified that F&C Asset Management has
ceased to have a notifiable interest in the Company.



                                    - ends -





For further information please contacts:



Alliance Pharma plc

John Dawson, CEO

01249 466966



Beattie Financial

Mike Wort/John Moriarty

020 7398 3300





About Alliance Pharma



Alliance Pharma, founded in 1996, is an AIM listed emerging speciality
pharmaceutical company based in Chippenham, Wiltshire.  The company has a strong
track record of acquiring the rights to established niche brands and owns, or
shares, the rights to 31 branded pharmaceutical products and is currently
exploring several opportunities to expand the range.  In November 2003 the
company acquired Peerless Technology Group Plc constituting a reverse takeover
under the AIM rules.






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