Major Interest in Shares

RNS Number : 5723I

Alliance Pharma PLC

15 March 2010

For immediate release

15 March 2010

ALLIANCE PHARMA PLC

("the Company")

Major Interest in Shares

Alliance Pharma plc (AIM: APH), the speciality pharmaceutical company, was informed on 15 March 2010 that Nigel Wray purchased, on 12 March 2010, 200,000 ordinary shares of 1p each in the Company.

Mr Wray's resultant shareholding is 24,519,995 ordinary shares, equivalent to 11.04% of the Company's issued share capital.

Mr Wray's ordinary shares are held as follows:

Nominee

Number of ordinary shares

Pershing Keen Nominees Limited

Smith & Williamson Nominees Limited

Roy Nominees Limited

8,905,407

50,000

15,564,588

For further information:

Alliance Pharma plc	+ 44 (0) 1249 466966
John Dawson, Chief Executive
Richard Wright, Finance Director
www.alliancepharma.co.uk

Buchanan Communications	+ 44 (0) 20 7466 5000
Mark Court / Stasa Filiplic / Jennie Spivey

Numis Securities Limited	+ 44 (0) 20 7260 1000
Nominated Adviser: Michael Meade / Brent Nabbs
Corporate Broking: David Poutney