Notice of Interests in Shares

Alliance Pharma PLC
24 June 2005


For Immediate Release                                              24 June 2005

                              Alliance Pharma Plc
                                        
                    Notification of Major Interests in Shares
                                        
            Nigel Wray acquires additional shares in Alliance Pharma

On 23 June 2005, the company was notified by Nigel Wray that he has purchased 
an additional 3,250,000 shares at 15p in the company bringing his total holdings 
in Alliance Pharma to 9,605,407 ordinary shares or 6.58% of the issued share 
capital.

                                     -ENDS-

For further information:

Alliance Pharma plc                                        + 44 (0) 1249 466966
John Dawson, Chief Executive
Maddy Scott, Finance Director
www.alliancepharma.co.uk

Numis Securities                                          + 44 (0) 20 7776 1500
David Poutney

Buchanan Communications                                   + 44 (0) 20 7466 5000
Mark Court/Lisa Baderoon/Rebecca Skye Dietrich




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