Notification of Shares

Alliance Pharma PLC
13 July 2005


For Immediate Release                                               13 July 2005

                              Alliance Pharma Plc

                    Notification of Major Interests in Shares


On 8 July 2005, the company was notified by Artemis Investment Management
Limited and certain of its subsidiary companies have a notifiable interest of
5,650,000 shares, representing 3.83% of the issued share capital of Alliance
Pharma.

                                   -ENDS-


For further information:

Alliance Pharma plc                                         + 44 (0) 1249 466966
John Dawson, Chief Executive
Maddy Scott, Finance Director
www.alliancepharma.co.uk

Numis Securities                                           + 44 (0) 20 7776 1500
David Poutney

Buchanan Communications                                    + 44 (0) 20 7466 5000
Mark Court/Lisa Baderoon/Rebecca Skye Dietrich


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