Annual Information Update

AstraZeneca PLC
29 March 2007



                                 ASTRAZENECA PLC

                           ANNUAL INFORMATION UPDATE


As required under the Prospectus (Directive 2003/71/EC) Regulations 2005 and
paragraph 5.2 of the Prospectus Rules, and following publication of the Annual
Report and Form 20-F Information on 1 March 2007, AstraZeneca PLC is presenting
its Annual Information Update in relation to information that has been published
or made available to the public between 28 March 2006 and 28 March 2007.


This Annual Information Update is also being made available on the Investors
section of our website, www.astrazeneca.com.



The information referred to in this Annual Information Update was correct at the
time it was published but may now be out of date.



1. Announcements made via a RIS



The documents listed below were published via a Regulatory Information Service
on or around the dates indicated.


Date             Description of Contents of Announcement

28/03/07         Director/PDMR Shareholding
28/03/07         Filing of Form 20-F
28/03/07         Transaction in Own Shares
27/03/07         Transaction in Own Shares
26/03/07         Director/PDMR Shareholding
26/03/07         Transaction in Own Shares
23/03/07         Transaction in Own Shares
22/03/07         Transaction in Own Shares
21/03/07         Holding(s) in Company
21/03/07         Holding(s) in Company
21/03/07         Transaction in Own Shares
20/03/07         Notice of AGM - Replacement
20/03/07         Transaction in Own Shares
19/03/07         ARISE Study
19/03/07         Transaction in Own Shares
16/03/07         Transaction in Own Shares
15/03/07         Transaction in Own Shares
14/03/07         Transaction in Own Shares
13/03/07         Transaction in Own Shares
12/03/07         Transaction in Own Shares
09/03/07         Transaction in Own Shares
08/03/07         Transaction in Own Shares
07/03/07         Transaction in Own Shares
06/03/07         Transaction in Own Shares
05/03/07         Transaction in Own Shares
02/03/07         Transaction in Own Shares
01/03/07         Annual Report and Accounts
01/03/07         Transaction in Own Shares
28/02/07         Director/PDMR Shareholding
28/02/07         Transaction in Own Shares
27/02/07         Director/PDMR Shareholding
27/02/07         Director/PDMR Shareholding
27/02/07         Transaction in Own Shares
26/02/07         Transaction in Own Shares
23/02/07         Transaction in Own Shares
22/02/07         Transaction in Own Shares
21/02/07         Transaction in Own Shares
20/02/07         Transaction in Own Shares
19/02/07         Transaction in Own Shares
16/02/07         Transaction in Own Shares
15/02/07         Transaction in Own Shares
14/02/07         Transaction in Own Shares
13/02/07         Transaction in Own Shares
12/02/07         Transaction in Own Shares
09/02/07         Transaction in Own Shares
08/02/07         Transaction in Own Shares
07/02/07         Holding(s) in Company
07/02/07         Transaction in Own Shares
06/02/07         Transaction in Own Shares
02/02/07         Transaction in Own Shares
01/02/07         Final Results Part 3 of 3
01/02/07         Final Results Part 2 of 3
01/02/07         Final Results Part 1 of 3
01/02/07         Acquisition
31/01/07         Notice of Results
19/01/07         Total Voting Rights
11/01/07         Collaboration with BMS
20/12/06         Transparency Directive
19/12/06         Director/PDMR Shareholding
19/12/06         EPO Patent Decision
18/12/06         Holding(s) in Company
15/12/06         Holding(s) in Company
15/12/06         Transaction in Own Shares
13/12/06         Transaction in Own Shares
12/12/06         Transaction in Own Shares
11/12/06         Transaction in Own Shares
08/12/06         Transaction in Own Shares
05/12/06         Holding(s) in Company
04/12/06         Transaction in Own Shares
01/12/06         Transaction in Own Shares
30/11/06         Transaction in Own Shares
29/11/06         Transaction in Own Shares
28/11/06         Transaction in Own Shares
27/11/06         Transaction in Own Shares
24/11/06         Transaction in Own Shares
23/11/06         Transaction in Own Shares
22/11/06         Toprol-XL Authorised Generic
22/11/06         Transaction in Own Shares
21/11/06         Transaction in Own Shares
20/11/06         Transaction in Own Shares
17/11/06         Transaction in Own Shares
16/11/06         Transaction in Own Shares
15/11/06         Transaction in Own Shares
14/11/06         Transaction in Own Shares
13/11/06         Transaction in Own Shares
10/11/06         Transaction in Own Shares
09/11/06         Transaction in Own Shares
08/11/06         Transaction in Own Shares
07/11/06         Transaction in Own Shares
06/11/06         Transaction in Own Shares
03/11/06         Transaction in Own Shares
02/11/06         Transaction in Own Shares
30/10/06         Holding(s) in Company
27/10/06         Share Repurchase Programme
27/10/06         Transaction in Own Shares
26/10/06         3rd Quarter Results - Part 2
26/10/06         3rd Quarter Results - Part 1
26/10/06         NXY-059 SAINT II Results
26/10/06         Transaction in Own Shares
25/10/06         Notice of Results
25/10/06         Transaction in Own Shares
24/10/06         Director/PDMR Shareholding
24/10/06         Transaction in Own Shares
23/10/06         Seroquel Bipolar
23/10/06         Transaction in Own Shares
20/10/06         Transaction in Own Shares
19/10/06         Seroquel SR
19/10/06         Transaction in Own Shares
18/10/06         Transaction in Own Shares
17/10/06         Transaction in Own Shares
16/10/06         Transaction in Own Shares
13/10/06         Transaction in Own Shares
12/10/06         Transaction in Own Shares
11/10/06         Transaction in Own Shares
10/10/06         Transaction in Own Shares
09/10/06         Symbicort
09/10/06         Transaction in Own Shares
06/10/06         Transaction in Own Shares
05/10/06         Transaction in Own Shares
04/10/06         Transaction in Own Shares
03/10/06         Transaction in Own Shares
28/09/06         Transaction in Own Shares
27/09/06         Transaction in Own Shares
25/09/06         Transaction in Own Shares
22/09/06         Director/PDMR Shareholding
22/09/06         Transaction in Own Shares
21/09/06         Share Repurchase Programme
20/09/06         Transaction in Own Shares
19/09/06         Transaction in Own Shares
15/09/06         Transaction in Own Shares
14/09/06         Transaction in Own Shares
13/09/06         Transaction in Own Shares
12/09/06         Transaction in Own Shares
11/09/06         Transaction in Own Shares
08/09/06         Transaction in Own Shares
07/09/06         Transaction in Own Shares
06/09/06         Transaction in Own Shares
01/09/06         Transaction in Own Shares
31/08/06         Transaction in Own Shares
29/08/06         Director/PDMR Shareholding
25/08/06         Director/PDMR Shareholding
25/08/06         Transaction in Own Shares
24/08/06         Transaction in Own Shares
23/08/06         Transaction in Own Shares
22/08/06         Holding(s) in Company
22/08/06         Offer for Cambridge Antibody
21/08/06         Holding(s) in Company
18/08/06         Holding(s) in Company
18/08/06         Director/PDMR Shareholding
17/08/06         Director/PDMR Shareholding
17/08/06         Transaction in Own Shares
16/08/06         Holding(s) in Company
16/08/06         Transaction in Own Shares
14/08/06         Transaction in Own Shares
11/08/06         Transaction in Own Shares
10/08/06         Transaction in Own Shares
09/08/06         Director/PDMR Shareholding
09/08/06         Transaction in Own Shares
07/08/06         Director/PDMR Shareholding
07/08/06         Transaction in Own Shares
03/08/06         Transaction in Own Shares
02/08/06         Agreement with Pozen Inc.
02/08/06         Transaction in Own Shares
01/08/06         Transaction in Own Shares
31/07/06         Transaction in Own Shares
28/07/06         Transaction in Own Shares
27/07/06         Interim Results - Part 2 of 2
27/07/06         Interim Results - Part 1 of 2
26/07/06         Notice of Results
26/07/06         Directorate Change
25/07/06         Holding(s) in Company
24/07/06         Symbicort
18/07/06         Seroquel SR
07/07/06         Offer for Cambridge Antibody
05/07/06         Agreement with Abbott
05/07/06         Holding(s) in Company
30/06/06         Offer for Cambridge Antibody
30/06/06         Transaction in Own Shares
28/06/06         Transaction in Own Shares
26/06/06         Transaction in Own Shares
22/06/06         Offer for Cambridge Antibody
21/06/06         Transaction in Own Shares
15/06/06         Transaction in Own Shares
13/06/06         Transaction in Own Shares
12/06/06         Transaction in Own Shares
08/06/06         Research Update - Part 2 of 2
08/06/06         Research Update - Part 1 of 2
07/06/06         Offer for Cambridge Antibody
01/06/06         Transaction in Own Shares
30/05/06         Transaction in Own Shares
25/05/06         Transaction in Own Shares
24/05/06         Rule 8.1 - Cambridge Antibody
24/05/06         Transaction in Own Shares
23/05/06         Director/PDMR Shareholding
23/05/06         AstraZeneca Offer for CAT
22/05/06         Transaction in Own Shares
19/05/06         Transaction in Own Shares
18/05/06         Transaction in Own Shares
17/05/06         Transaction in Own Shares
16/05/06         Transaction in Own Shares
15/05/06         Offer for Cambridge Antibody
15/05/06         Transaction in Own Shares
12/05/06         Transaction in Own Shares
11/05/06         Transaction in Own Shares
10/05/06         Transaction in Own Shares
09/05/06         AGM Resolutions
08/05/06         Transaction in Own Shares
05/05/06         Transaction in Own Shares
04/05/06         GALIDA
02/05/06         Director/PDMR Shareholding
27/04/06         Result of AGM
27/04/06         1st Quarter Results - 2 of 2
27/04/06         1st Quarter Results - 1 of 2
27/04/06         US Oncology Co-Promotion
26/04/06         Notice of Results
20/04/06         Holding(s) in Company
03/04/06         Transaction in Own Shares
31/03/06         Transaction in Own Shares
31/03/06         Transaction in Own Shares
29/03/06         Director/PDMR Shareholding
29/03/06         Transaction in Own Shares
28/03/06         Director/PDMR Shareholding
28/03/06         Director/PDMR Shareholding
28/03/06         Director/PDMR Shareholding
28/03/06         Director/PDMR Shareholding
28/03/06         Annual Information Update
28/03/06         Director/PDMR Shareholding
28/03/06         Transaction in Own Shares



All of the above documents are available for download on the Prices and News
section of the London Stock Exchange website, www.londonstockexchange.com.



2.  Documents filed at Companies House



All of the documents below were filed with the Registrar of Companies in England
and Wales on or around the dates indicated.


Date             Document type

28/03/07         Interim Accounts made up to 31/12/06
23/01/07         Form 169 - Return by a Company Purchasing its Own Shares
23/01/07         Form 169 - Return by a Company Purchasing its Own Shares
23/01/07         Form 169 - Return by a Company Purchasing its Own Shares
19/01/07         Form 169 - Return by a Company Purchasing its Own Shares
19/01/07         Form 169 - Return by a Company Purchasing its Own Shares
19/01/07         Form 169 - Return by a Company Purchasing its Own Shares
19/01/07         Form 169 - Return by a Company Purchasing its Own Shares
19/01/07         Form 169 - Return by a Company Purchasing its Own Shares
19/01/07         Form 169 - Return by a Company Purchasing its Own Shares
19/01/07         Form 169 - Return by a Company Purchasing its Own Shares
19/01/07         Form 88(2)R - Return of an Allotment of Shares
19/01/07         Form 88(2)R - Return of an Allotment of Shares
19/01/07         Form 88(2)R - Return of an Allotment of Shares
19/01/07         Form 88(2)R - Return of an Allotment of Shares
19/01/07         Form 88(2)R - Return of an Allotment of Shares
19/01/07         Form 88(2)R - Return of an Allotment of Shares
19/01/07         Form 88(2)R - Return of an Allotment of Shares
19/01/07         Form 88(2)R - Return of an Allotment of Shares
19/01/07         Form 88(2)R - Return of an Allotment of Shares
12/01/07         Form 288a - Director Appointed
11/01/07         Form 288a - Director Appointed
06/12/06         Form 169 - Return by a Company Purchasing its Own Shares
06/12/06         Form 169 - Return by a Company Purchasing its Own Shares
06/12/06         Form 169 - Return by a Company Purchasing its Own Shares
06/12/06         Form 169 - Return by a Company Purchasing its Own Shares
06/12/06         Form 169 - Return by a Company Purchasing its Own Shares
06/12/06         Form 169 - Return by a Company Purchasing its Own Shares
06/12/06         Form 169 - Return by a Company Purchasing its Own Shares
02/11/06         Interim Accounts made up to 30/09/06
01/11/06         Form 169 - Return by a Company Purchasing its Own Shares
01/11/06         Form 169 - Return by a Company Purchasing its Own Shares
01/11/06         Form 169 - Return by a Company Purchasing its Own Shares
01/11/06         Form 169 - Return by a Company Purchasing its Own Shares
01/11/06         Form 169 - Return by a Company Purchasing its Own Shares
01/11/06         Form 169 - Return by a Company Purchasing its Own Shares
17/10/06         Form 88(2)R - Return of an Allotment of Shares
17/10/06         Form 88(2)R - Return of an Allotment of Shares
17/10/06         Form 88(2)R - Return of an Allotment of Shares
17/10/06         Form 88(2)R - Return of an Allotment of Shares
17/10/06         Form 88(2)R - Return of an Allotment of Shares
17/10/06         Form 88(2)R - Return of an Allotment of Shares
17/10/06         Form 88(2)R - Return of an Allotment of Shares
17/10/06         Form 88(2)R - Return of an Allotment of Shares
17/10/06         Form 88(2)R - Return of an Allotment of Shares
28/09/06         Form 169  - Return by a Company Purchasing its Own Shares
28/09/06         Form 169 - Return by a Company Purchasing its Own Shares
28/09/06         Form 169 - Return by a Company Purchasing its Own Shares
28/09/06         Form 169 - Return by a Company Purchasing its Own Shares
29/09/06         Form 169 - Return by a Company Purchasing its Own Shares
29/09/06         Form 169 - Return by a Company Purchasing its Own Shares
29/09/06         Form 169 - Return by a Company Purchasing its Own Shares
14/08/06         Interim Accounts made up to 30/06/06
08/08/06         Form 88(2)R - Return of an Allotment of Shares
08/08/06         Form 88(2)R - Return of an Allotment of Shares
08/08/06         Form 88(2)R - Return of an Allotment of Shares
08/08/06         Form 88(2)R - Return of an Allotment of Shares
08/08/06         Form 88(2)R - Return of an Allotment of Shares
08/08/06         Form 88(2)R - Return of an Allotment of Shares
08/08/06         Form 88(2)R - Return of an Allotment of Shares
08/08/06         Form 88(2)R - Return of an Allotment of Shares
12/07/06         Form 169 - Return by a Company Purchasing its Own Shares
12/07/06         Form 169 - Return by a Company Purchasing its Own Shares
12/07/06         Form 169 - Return by a Company Purchasing its Own Shares
12/07/06         Form 169 - Return by a Company Purchasing its Own Shares
12/07/06         Form 169 - Return by a Company Purchasing its Own Shares
20/06/06         Form 88(2)R - Return of an Allotment of Shares
20/06/06         Form 88(2)R - Return of an Allotment of Shares
20/06/06         Form 88(2)R - Return of an Allotment of Shares
20/06/06         Form 88(2)R - Return of an Allotment of Shares
20/06/06         Form 88(2)R - Return of an Allotment of Shares
20/06/06         Form 88(2)R - Return of an Allotment of Shares
20/06/06         Form 88(2)R - Return of an Allotment of Shares
20/06/06         Form 88(2)R - Return of an Allotment of Shares
23/06/06         Form 363s - Return made up to 15/05/06
14/06/06         Form 169 - Return by a Company Purchasing its Own Shares
13/06/06         Resolution to disapply pre-emption rights, to give authority to allot shares and to give
                 authority to make market purchases of own shares
31/05/06         Interim Accounts made up to 30/03/06
26/05/06         Group of Companies' Accounts made up to 31/12/05
11/05/06         Form 288b - Director Resigned
19/05/06         Form 169 - Return by a Company Purchasing its Own Shares
19/05/06         Form 169 - Return by a Company Purchasing its Own Shares
19/05/06         Form 169 - Return by a Company Purchasing its Own Shares



All of the documents above are available for download from the Companies House
website at www.companieshouse.gov.uk, or can be obtained from Companies House,
Crown Way, Maindy, Cardiff, CF14 3UZ.



3. Documents submitted to the FSA



All the documents below were submitted to the FSA on or around the dates
indicated.


Date             Document

20/03/07         Notice of AGM 2007

28/02/07         Annual Report and Form 20-F Information 2006

28/02/07         Annual Review 2006

28/02/07         Summary CR Report 2006

09/05/06         Resolutions after AGM 2006




Documents submitted to the FSA can be viewed at the Document Viewing Facility
situated at The Financial Services Authority, 25 The North Colonnade, Canary
Wharf, London, E14 5HS.



The Notices of AGM, Annual Reports and Form 20-F Information, Annual Reviews and
Summary CR Reports are also available via the Investors section of our website,
www.astrazeneca.com.



4. Documents lodged with the Securities and Exchange Commission



The documents listed below were filed with the SEC on or around the dates
indicated.


Date             Document

27/03/07         Annual Reports

06/03/07         Quarterly Reports

06/03/07         Quarterly Reports

05/03/07         Quarterly Reports

12/02/07         Insider Trading

12/02/07         Insider Trading

06/02/07         Quarterly Reports

19/01/07         Quarterly Reports

05/12/06         Quarterly Reports

03/11/06         Quarterly Reports

02/10/06         Quarterly Reports

11/09/06         Quarterly Reports

22/08/06         Schedule to Tender Offer Statement for Cambridge Antibody

04/08/06         Quarterly Reports

10/07/06         Quarterly Reports

07/07/06         Schedule to Tender Offer Statement for Cambridge Antibody

30/06/06         Schedule to Tender Offer Statement for Cambridge Antibody

29/06/06         Annual Report of Employee Stock Purchase Savings Plans

26/06/06         Schedule to Tender Offer Statement for Cambridge Antibody

22/06/06         Schedule to Tender Offer Statement for Cambridge Antibody

21/06/06         Schedule to Tender Offer Statement for Cambridge Antibody

15/06/06         Schedule to Tender Offer Statement for Cambridge Antibody

09/06/06         Schedule to Tender Offer Statement for Cambridge Antibody

07/06/06         Schedule to Tender Offer Statement for Cambridge Antibody

02/06/06         Quarterly Reports

25/05/06         Schedule to Tender Offer Statement for Cambridge Antibody

24/05/06         Schedule to Tender Offer Statement for Cambridge Antibody

23/05/06         Schedule to Tender Offer Statement for Cambridge Antibody

23/05/06         Form NO ACT

23/05/06         Form NO ACT

15/05/06         Schedule to Tender Offer Statement for Cambridge Antibody

15/05/06         Schedule 13D/A - Cambridge Antibody

03/05/06         Quarterly Reports

04/04/06         Quarterly Reports

23/03/06         Annual Reports




All of the documents above are available for viewing on the Investor section of
our website, www.astrazeneca.com.



5.  Further Information



Further information about AstraZeneca PLC can be found at our website,
www.astrazeneca.com.














                      This information is provided by RNS
            The company news service from the London Stock Exchange