Annual Information Update

RNS Number : 0675V

AstraZeneca PLC

22 May 2008

ASTRAZENECA PLC

ANNUAL INFORMATION UPDATE

As required under the Prospectus (Directive 2003/71/EC) Regulations 2005 and paragraph 5.2 of the Prospectus Rules, and following publication of the Annual Report and Form 20-F Information on 6 March 2008, AstraZeneca PLC is presenting its Annual Information Update in relation to information that has been published or made available to the public between 28 March 2007 and 21 May 2008.

This Annual Information Update is also being made available on the Investors section of our website, www.astrazeneca.com.

The information referred to in this Annual Information Update was correct at the time it was published but may now be out of date.

1. Announcements made via a RIS

The documents listed below were published via a Regulatory Information Service on or around the dates indicated.

Date	Description of Contents of Announcement

28/03/07	Transaction in Own Shares
28/03/07	Filing of Form 20-F
28/03/07	Director/PDMR Shareholding
29/03/07	Transaction in Own Shares
29/03/07	Annual Information Update
30/03/07	Transaction in Own Shares
02/04/07	Transaction in Own Shares
02/04/07	Director/PDMR Shareholding
02/04/07	Director/PDMR Shareholding
02/04/07	Director/PDMR Shareholding
02/04/07	Director/PDMR Shareholding
03/04/07	Transaction in Own Shares
04/04/07	Transaction in Own Shares
05/04/07	Transaction in Own Shares
10/04/07	Transaction in Own Shares
10/04/07	Holding(s) in Company
11/04/07	Transaction in Own Shares
12/04/07	Transaction in Own Shares
12/04/07	Directorate Change
13/04/07	Transaction in Own Shares
16/04/07	Transaction in Own Shares
17/04/07	Transaction in Own Shares
18/04/07	Transaction in Own Shares
19/04/07	Transaction in Own Shares
20/04/07	Transaction in Own Shares


23/04/07	Transaction in Own Shares
23/04/07	Acquisition - MedImmune, Inc
23/04/07	First Quarter Results
23/04/07	Research UpDate - AGI 1067
24/04/07	Transaction in Own Shares
25/04/07	Transaction in Own Shares
25/04/07	Director/PDMR Shareholding
26/04/07	Transaction in Own Shares
26/04/07	AGM Poll Results
27/04/07	Transaction in Own Shares
30/04/07	Transaction in Own Shares
01/05/07	Transaction in Own Shares
02/05/07	Transaction in Own Shares
03/05/07	Transaction in Own Shares
03/05/07	MedImmune Offer Document Posted
04/05/07	Transaction in Own Shares
05/05/07	AGM Resolutions
18/05/07	Seroquel XR
24/05/07	Transaction in Own Shares
25/05/07	Transaction in Own Shares
30/05/07	Transaction in Own Shares
30/05/07	Holding(s) in Company
31/05/07	Total Voting Rights
01/06/07	MedImmune Offer UpDate
04/06/07	Transaction in Own Shares
06/06/07	Transaction in Own Shares
06/06/07	Directorate Change
06/06/07	MedImmune Offer UpDate
08/06/07	Transaction in Own Shares
11/06/07	Transaction in Own Shares
18/06/07	Holding(s) in Company
19/06/07	MedImmune Offer UpDate
21/06/07	Transaction in Own Shares
25/06/07	Transaction in Own Shares
25/06/07	Holding(s) in Company
29/06/07	Share RePurchase Programme
29/06/07	Total Voting Rights
03/07/07	Transaction in Own Shares
04/07/07	Transaction in Own Shares
05/07/07	Transaction in Own Shares
06/07/07	Transaction in Own Shares
09/07/07	Transaction in Own Shares
10/07/07	Transaction in Own Shares
11/07/07	Transaction in Own Shares
12/07/07	Transaction in Own Shares
13/07/07	Transaction in Own Shares
16/07/07	Transaction in Own Shares
17/07/07	Transaction in Own Shares


18/07/07	Transaction in Own Shares
19/07/07	Transaction in Own Shares
20/07/07	Transaction in Own Shares
23/07/07	Transaction in Own Shares
24/07/07	Transaction in Own Shares
25/07/07	Transaction in Own Shares
25/07/07	Directorate Change
25/07/07	Notice of Results
26/07/07	Transaction in Own Shares
26/07/07	Half Year Results
27/07/07	Transaction in Own Shares
30/07/07	Transaction in Own Shares
30/07/07	Director/PDMR Shareholding
31/07/07	Transaction in Own Shares
01/08/07	Transaction in Own Shares
01.08/07	Total Voting Rights
02/08/07	Transaction in Own Shares
03/08/07	Transaction in Own Shares
06/08/07	Transaction in Own Shares
07/08/07	Transaction in Own Shares
08/08/07	Transaction in Own Shares
09/08/07	Transaction in Own Shares
10/08/07	Transaction in Own Shares
13/08/07	Transaction in Own Shares
14/08/07	Transaction in Own Shares
15/08/07	Transaction in Own Shares
16/08/07	Transaction in Own Shares
17/08/07	Transaction in Own Shares
20/08/07	Transaction in Own Shares
21/08/07	Transaction in Own Shares
22/08/07	Transaction in Own Shares
23/08/07	Transaction in Own Shares
24/08/07	Transaction in Own Shares
28/08/07	Transaction in Own Shares
29/08/07	Transaction in Own Shares
30/08/07	Transaction in Own Shares
31/08/07	Transaction in Own Shares
31/08/07	Total Voting Rights
03/08/07	Transaction in Own Shares
04/09/07	Transaction in Own Shares
05/09/07	Transaction in Own Shares
06/09/07	Transaction in Own Shares
06/09/07	Bond Issue
07/09/07	Transaction in Own Shares
10/09/07	Transaction in Own Shares
11/09/07	Transaction in Own Shares
11/09/07	EMTN Base Prospectus
12/09/07	Transaction in Own Shares
13/09/07	Transaction in Own Shares
13/09/07	EuroBond Issue
14/09/07	Transaction in Own Shares
17/09/07	Transaction in Own Shares
18/09/07	Transaction in Own Shares
19/09/07	Transaction in Own Shares
19/09/07	Transaction in Own Shares [Amended]
20/09/07	Transaction in Own Shares
20/09/07	Transaction in Own Shares [Amended]
21/09/07	Transaction in Own Shares
24/09/07	Transaction in Own Shares
25/09/07	Transaction in Own Shares
26/09/07	Transaction in Own Shares
27/09/07	Transaction in Own Shares
28/09/07	Transaction in Own Shares
28/09/07	Directorate Change
28/09/07	Total Voting Rights
01/10/07	Transaction in Own Shares
02/10/07	Transaction in Own Shares
03/10/07	Transaction in Own Shares
04/10/07	Transaction in Own Shares
05/10/07	Transaction in Own Shares
08/10/07	Transaction in Own Shares
09/10/07	Transaction in Own Shares
09/10/07	European Patent Office Ruling on Nexium
10/10/07	Transaction in Own Shares
11/10/07	Transaction in Own Shares
12/10/07	Transaction in Own Shares
15/10/07	Transaction in Own Shares
16/10/07	Transaction in Own Shares
17/10/07	Transaction in Own Shares
18/10/07	Transaction in Own Shares
18/10/07	European Patent Office Ruling on Symbicort
19/10/07	Transaction in Own Shares
22/10/07	Transaction in Own Shares
23/10/07	Transaction in Own Shares
24/10/07	Transaction in Own Shares
25/10/07	Transaction in Own Shares
26/10/07	Transaction in Own Shares
29/10/07	Transaction in Own Shares
30/10/07	Transaction in Own Shares
31/10/07	Transaction in Own Shares
31/10/07	Notice of Results
31/10/07	Total Voting Rights
01/11/07	Transaction in Own Shares
01/11/07	Crestor ANDA
01/11/07	Third Quarter and Nine Months Results
02/11/07	Transaction in Own Shares
05/11/07	Transaction in Own Shares
06/11/07	Transaction in Own Shares
06/11/07	EMTN Supplementary Prospectus
07/11/07	Pricing of Bond Issue
08/11/07	Transaction in Own Shares
09/11/07	Transaction in Own Shares
09/11/07	Crestor Atherosclerosis
13/11/07	Transaction in Own Shares
19/11/07	Transaction in Own Shares
19/11/07	Director/PDMR Shareholding
20/11/07	Transaction in Own Shares
21/11/07	Transaction in Own Shares
27/11/07	Transaction in Own Shares
29/11/07	Transaction in Own Shares
30/11/07	Total Voting Rights
05/12/07	Director/PDMR Shareholding
06/12/07	Holding(s) in Company
07/12/07	Research Update
11/12/07	Transaction in Own Shares
12/12/07	Transaction in Own Shares
12/12/07	Crestor ANDAs
13/12/07	Transaction in Own Shares
14/12/07	Transaction in Own Shares
20/12/07	Holding(s) in Company
02/01/08	Total Voting Rights
08/01/08	Director/PDMR Shareholding
30/01/08	Notice of Results
31/01/08	Full Year Results 2007
31/01/08	Total Voting Rights
04/02/08	Regulatory Submission
18/02/08	Directorate Change
22/02/08	Alabama Pricing Case Result
27/02/08	Research UpDate : Recentin
27/02/08	Director/PDMR Shareholding
27/02/08	Director/PDMR Shareholding
27/02/08	Director/PDMR Shareholding
28/02/08	Arrangement with Merck
29/02/08	Seroquel XR sNDA
29/02/08	Total Voting Rights
06/03/08	Annual Report and Accounts
12/03/08	Seroquel Patent Litigation
12/03/08	Filing of Form 20F
26/03/08	Director/PDMR Shareholding
26/03/08	Director/PDMR Shareholding
26/03/08	Director/PDMR Shareholding
31/03/08	Crestor Jupiter Study
31/03/08	Total Voting Right
31/03/08	Director/PDMR Shareholding
31/03/08	Director/PDMR Shareholding
31/03/08	Director/PDMR Shareholding
31/03/08	Director/PDMR Shareholding
15/04/08	Nexium and Ranbaxy
23/04/08	Notice of Results
24/04/08	Results of AGM
24/04/08	First Quarter Results
30/04/08	Symbicort
30/04/08	Total Voting Rights
06/05/08	Symbicort
09/05/08	Transaction in Own Shares
12/05/08	Transaction in Own Shares
14/05/08	Seroquel
22/05/08	Supplementary Prospectus

All of the above documents are available for download on the Prices and News section of the London Stock Exchange website, www.londonstockexchange.com.

Documents filed at Companies House

All of the documents below were filed with the Registrar of Companies in England and Wales on or around the dates indicated.

Date	Document type

28/03/07	Interim Accounts made up to 31/12/06
18/05/07	288b - Director Resigned
18/05/07	288b - Director Resigned
18/05/07	288b - Director Resigned
29/05/07	Resolution
15/06/07	363s - Annual Return
26/06/07	Interim Accounts made up to 31/03/07
11/07/07	88(2) R
11/07/07	88(2) R
11/07/07	88(2) R
11/07/07	88(2) R
11/07/07	88(2) R
11/07/07	88(2) R
11/07/07	88(2) R
08/08/07	Interim Accounts made up to 30/06/07
10/08/07	Amended Group of Companies' Accounts made up to 31/12/06
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
05/11/07	288a - New Director Appointed
08/11/07	Interim Accounts made up to 30/09/07
21/11/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
25/10/07	169
03/12/07	288b - Director Resigned
17/12/07	288a - New Director Appointed
17/12/07	288a - New Director Appointed
19/12/07	288a - New Director Appointed
27/12/07	288a - New Director Appointed
17/03/08	ML28 Transferred Doc from AstraZeneca UK PLC
18/03/08	169 - capitals not rolled up
18/03/08	169 - capitals not rolled up
18/03/08	169 - capitals not rolled up
18/03/08	169 - capitals not rolled up
18/03/08	169 - capitals not rolled up
18/03/08	169 - capitals not rolled up
18/03/08	169 - capitals not rolled up
18/03/08	169 - capitals not rolled up
18/03/08	169 - capitals not rolled up
18/03/08	169 - capitals not rolled up
18/03/08	169 - capitals not rolled up
18/03/08	169 - capitals not rolled up
18/03/08	169 - capitals not rolled up
18/03/08	169 - capitals not rolled up
18/03/08	169 - capitals not rolled up
18/03/08	169 - capitals not rolled up
18/03/08	169 - capitals not rolled up
18/03/08	169 - capitals not rolled up
18/03/08	169 - capitals not rolled up
18/03/08	169 - capitals not rolled up
18/03/08	169 - capitals not rolled up
01/05/08	Resolutions after AGM 2008
01/05/08	Articles of Association
13/05/08	288a - New Director Appointed

All of the documents above are available for download from the Companies House website at www.companieshouse.gov.uk, or can be obtained from Companies House, Crown Way, Maindy, Cardiff, CF14 3UZ.

3. Documents submitted to the FSA

All the documents below were submitted to the FSA on or around the dates indicated.

Date	Document
21/08/07	Form 20-F 2005
21/08/07	Form 20-F 2006
05/09/07	Form 6-K
10/09/07	Prospectus
05/11/07	Third Quarter and Nine Month Results 2007
06/11/07	Supplementary Prospectus
06/03/08	Annual Report and Form 20-F Information 2007
06/03/08	Notice of AGM 2008 and Shareholders' Circular
06/03/08	Shareholder Letter 2008
01/05/08	Resolutions after AGM 2008
01/05/08	Articles of Association
21/05/08	Supplementary Prospectus

Documents submitted to the FSA can be viewed at the Document Viewing Facility situated at The Financial Services Authority, 25 The North Colonnade, Canary Wharf, London, E14 5HS.

The Notices of AGM, Annual Reports and Form 20-F Information, Annual Reviews and Summary CR Reports are also available via the Investors section of our website, www.astrazeneca.com.

4. Documents lodged with the Securities and Exchange Commission

The documents listed below were filed with the SEC on or around the dates indicated.

Date	Document

03/04/07	Quarterly Reports
26/04/07	Quarterly Reports
04/05/07	Quarterly Reports
05/06/07	Quarterly Reports
13/06/07	Form SC 13D
27/06/07	Annual Report of Employee Stock Purchase Savings Plans
06/07/07	Quarterly Reports
30/07/07	Quarterly Reports
31/08/07	Quarterly Reports
31/08/07	Form F-3ASR
04/09/07	Form 424B3 : Form of Prospectus
04/09/07	Quarterly Reports
06/09/07	Form FWP : Free Writing Prospectus
07/09/07	Form 424B2 : Form of Prospectus
11/09/07	Form 8-A12B : Registration
12/09/07	Form CERTNYS
20/09/07	Form 8-A12B/A : Registration : Amendment No 1
04/10/07	Quarterly Reports
02/11/07	Quarterly Reports
10/12/07	Quarterly Reports
04/01/08	Quarterly Reports
12/02/08	Form SC 13G/A : Insider Trading
12/02/08	Quarterly Reports
13/02/08	Form SC 13G/A : Insider Trading
04/03/08	Quarterly Reports
07/02/08	Quarterly Reports
12/03/08	Form 20-F
03/04/08	Quarterly Reports
07/05/08	Quarterly Reports