Capital Group

AstraZeneca PLC
14 January 2003


COMPANIES ACT 1985 SECTION 198
DISCLOSURE OF INTEREST IN VOTING SHARES IN PUBLIC COMPANIES


ON 14 JANUARY 2003 WE WERE INFORMED BY THE CAPITAL GROUP COMPANIES, INC., A
REGISTERED INVESTMENT MANAGER IN THE U.S., THAT ON 10 JANUARY 2003 ITS INTEREST
IN THE USD0.25 ORDINARY SHARES OF ASTRAZENECA PLC HAD DECREASED TO 204,812,653
SHARES (11.92 PER CENT OF THE ISSUED ORDINARY CAPITAL) FROM THE PREVIOUSLY
NOTIFIED LEVEL OF 208,550,628 SHARES (12.13 PER CENT).


G H R MUSKER
COMPANY SECRETARY
14 JANUARY 2003


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