Director/PDMR Shareholding

RNS Number : 1992L

AstraZeneca PLC

30 April 2010

Transactions by Persons Discharging Managerial Responsibilities

Disclosure Rule DTR 3.1.4

We hereby inform you that on 30 April 2010 the following Directors of the Company notified us that, on 30 April 2010, they purchased AstraZeneca PLC Ordinary Shares of $0.25 each.

Name of Director	Number of shares purchased	Purchase price	Number of shares held following purchase	Percentage of shares in issue
Louis Schweitzer	1,299	2872.5p	6,655	0.0005
Jane Henney	275	2872.5p	1,062	0.00007
Rudy Markham	271	2872.5p	1,691	0.0001
Nancy Rothwell	275	2872.5p	1,062	0.00007