Transaction by Persons Discharging Managerial Responsibilities
We hereby inform you that on 24 May 2010, the interest of Tony Zook, a person discharging managerial responsibilities, in the shares of AstraZeneca PLC has changed as detailed below. Tony Zook has interests in the American Depositary Shares (ADSs) of AstraZeneca PLC. One ADS equals one Ordinary Share.
The change in interest relates to a previously announced award made in May 2008 under the AstraZeneca Restricted Share Plan, whereby, in accordance with the terms of the award, Tony Zook has now become beneficially entitled to 8,710 of the 34,841 ADSs originally awarded. After certain mandatory tax deductions, Mr Zook has received 5,150 ADSs into a personal brokerage account.
The market price of AstraZeneca ADSs on 21 May 2010, the last trading day prior to the vesting, was US$41.57.
A C N Kemp
Company Secretary
25 May 2010