Transaction by Person Discharging Managerial Responsibilities
Disclosure Rule DTR 3.1.4
We hereby inform you that on 1 November 2010, Marcus Wallenberg, a Director of the Company, notified us that he is no longer deemed to have an interest in 3,618 shares in the Company held by a family member, who is no longer a connected person.
Accordingly, Marcus Wallenberg now has a total interest in 63,646 AstraZeneca PLC Ordinary Shares of USD0.25 each, which represents approximately 0.004% of the issued ordinary capital of the Company.
A C N Kemp
Company Secretary
2 November 2010
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