Transaction by Persons Discharging Managerial Responsibilities
Disclosure Rule DTR 3.1.4
We hereby inform you that on 26 May 2009, the interest of Tony Zook, a person discharging managerial responsibilities, in the shares of AstraZeneca PLC has changed as detailed below. Tony Zook has interests in the American Depositary Shares (ADSs) of AstraZeneca PLC. One ADS equals one Ordinary Share.
The change in interest relates to a previously announced award made in May 2008 under the AstraZeneca Restricted Share Plan, whereby, in accordance with the terms of the award, Tony Zook has now become beneficially entitled to 8,710 of the 34,841 ADSs originally awarded. After certain mandatory tax deductions, Mr Zook has received 5,017 ADSs into a personal brokerage account.
The market price of AstraZeneca ADSs on 26 May 2009 was US$41.35.
A C N Kemp
Company Secretary
27 May 2009