Transaction by Persons Discharging Managerial Responsibilities
Disclosure Rule DTR 3.1.4
The interest of Simon Lowth, a Director of the Company, in AstraZeneca PLC Ordinary Shares of $0.25 each, has changed as detailed below.
On 24 February 2012, Mr Lowth was allocated 9,001 shares under the previously disclosed arrangements relating to the payment of annual bonuses whereby he is required to defer a portion of the bonus earned into shares for a period of three years. The shares were allocated at a price of 2851 pence per share. Mr Lowth will become beneficially entitled to these shares on 24 February 2015.
As a result of this transaction, Mr Lowth has an interest in 270,364 Ordinary Shares, which represent approximately 0.02% of the Company's issued ordinary capital.
A C N Kemp
Company Secretary
27 February 2012