Director Shareholding

AstraZeneca PLC
22 December 2000


DEALING BY DIRECTORS
COMPANIES ACT 1985 SECTION 324/329

ASTRAZENECA PLC ANNOUNCES THAT ON 21 DECEMBER 2000 IT WAS NOTIFIED BY
PROFESSOR ERNA MOLLER, A DIRECTOR OF THE COMPANY, THAT ON 6 DECEMBER 2000 SHE
PURCHASED 600 ASTRAZENECA ORDINARY USD0.25 SHARES AT SEK471.50 PER SHARE. 
THIS PURCHASE BRINGS PROFESSOR MOLLER'S TOTAL INTEREST TO 2,718 SHARES WHICH
REPRESENTS LESS THAN 0.001 PER CENT OF THE ISSUED SHARES.

G H R MUSKER
COMPANY SECRETARY