Director Shareholding

AstraZeneca PLC 17 November 2000 DEALING BY DIRECTORS COMPANIES ACT 1985 SECTION 324/329 WE HEREBY CONFIRM THAT ON 16 NOVEMBER 2000 SIR DAVID BARNES, A DIRECTOR OF ASTRAZENECA PLC, ACQUIRED AN INTEREST IN THE USD0.25 ORDINARY SHARES OF THE COMPANY. THIS INTEREST, WHICH IS REGISTERED IN SIR DAVID'S OWN NAME, ARISES AS A RESULT OF AN ALLOCATION OF ASTRAZENECA SHARES TO PARTICIPANTS IN THE COMPANY'S EXECUTIVE SHARE OPTION SCHEMES. IMMEDIATELY FOLLOWING THE ACQUISITION SOME OF THE SHARES WERE SOLD BY THE COMPANY ON BEHALF OF SIR DAVID IN ORDER TO MEET AN IMMEDIATE INCOME TAX LIABILITY ARISING ON THE ALLOCATION OF THE SHARES. NAME OF DIRECTOR NUMBER OF NUMBER OF TOTAL PERCENTAGE OF SHARES SHARES SOLD INTEREST ISSUED SHARES ACQUIRED SIR DAVID BARNES 1,007 224 217,634 0.012 THE PRICE AT WHICH THE SHARES WERE ACQUIRED AND SOLD WAS 3236P. G H R MUSKER COMPANY SECRETARY

Companies

AstraZeneca (AZN)
UK 100